{\rtf1\adeflang1025\ansi\ansicpg1250\uc1\adeff0\deff0\stshfdbch0\stshfloch0\stshfhich0\stshfbi0\deflang1051\deflangfe1051\themelang1051\themelangfe0\themelangcs0{\fonttbl{\f0\fbidi \froman\fcharset238\fprq2{\*\panose 02020603050405020304}Times New Roman{\*\falt Times New Roman};}
{\f2\fbidi \fmodern\fcharset238\fprq1{\*\panose 02070309020205020404}Courier New;}{\f3\fbidi \froman\fcharset2\fprq2{\*\panose 05050102010706020507}Symbol;}{\f10\fbidi \fnil\fcharset2\fprq2{\*\panose 05000000000000000000}Wingdings;}
{\f34\fbidi \froman\fcharset238\fprq2{\*\panose 02040503050406030204}Cambria Math;}{\f38\fbidi \fswiss\fcharset238\fprq2{\*\panose 020b0604030504040204}Tahoma{\*\falt Tahoma};}
{\f39\fbidi \fswiss\fcharset238\fprq2{\*\panose 00000000000000000000}Arial Narrow;}{\flomajor\f31500\fbidi \froman\fcharset238\fprq2{\*\panose 02020603050405020304}Times New Roman{\*\falt Times New Roman};}
{\fdbmajor\f31501\fbidi \froman\fcharset238\fprq2{\*\panose 02020603050405020304}Times New Roman{\*\falt Times New Roman};}{\fhimajor\f31502\fbidi \froman\fcharset238\fprq2{\*\panose 02040503050406030204}Cambria;}
{\fbimajor\f31503\fbidi \froman\fcharset238\fprq2{\*\panose 02020603050405020304}Times New Roman{\*\falt Times New Roman};}{\flominor\f31504\fbidi \froman\fcharset238\fprq2{\*\panose 02020603050405020304}Times New Roman{\*\falt Times New Roman};}
{\fdbminor\f31505\fbidi \froman\fcharset238\fprq2{\*\panose 02020603050405020304}Times New Roman{\*\falt Times New Roman};}{\fhiminor\f31506\fbidi \fswiss\fcharset238\fprq2{\*\panose 020f0502020204030204}Calibri;}
{\fbiminor\f31507\fbidi \froman\fcharset238\fprq2{\*\panose 02020603050405020304}Times New Roman{\*\falt Times New Roman};}{\f42\fbidi \froman\fcharset0\fprq2 Times New Roman{\*\falt Times New Roman};}
{\f41\fbidi \froman\fcharset204\fprq2 Times New Roman Cyr{\*\falt Times New Roman};}{\f43\fbidi \froman\fcharset161\fprq2 Times New Roman Greek{\*\falt Times New Roman};}{\f44\fbidi \froman\fcharset162\fprq2 Times New Roman Tur{\*\falt Times New Roman};}
{\f45\fbidi \froman\fcharset177\fprq2 Times New Roman (Hebrew){\*\falt Times New Roman};}{\f46\fbidi \froman\fcharset178\fprq2 Times New Roman (Arabic){\*\falt Times New Roman};}
{\f47\fbidi \froman\fcharset186\fprq2 Times New Roman Baltic{\*\falt Times New Roman};}{\f48\fbidi \froman\fcharset163\fprq2 Times New Roman (Vietnamese){\*\falt Times New Roman};}{\f62\fbidi \fmodern\fcharset0\fprq1 Courier New;}
{\f61\fbidi \fmodern\fcharset204\fprq1 Courier New Cyr;}{\f63\fbidi \fmodern\fcharset161\fprq1 Courier New Greek;}{\f64\fbidi \fmodern\fcharset162\fprq1 Courier New Tur;}{\f65\fbidi \fmodern\fcharset177\fprq1 Courier New (Hebrew);}
{\f66\fbidi \fmodern\fcharset178\fprq1 Courier New (Arabic);}{\f67\fbidi \fmodern\fcharset186\fprq1 Courier New Baltic;}{\f68\fbidi \fmodern\fcharset163\fprq1 Courier New (Vietnamese);}{\f382\fbidi \froman\fcharset0\fprq2 Cambria Math;}
{\f381\fbidi \froman\fcharset204\fprq2 Cambria Math Cyr;}{\f383\fbidi \froman\fcharset161\fprq2 Cambria Math Greek;}{\f384\fbidi \froman\fcharset162\fprq2 Cambria Math Tur;}{\f387\fbidi \froman\fcharset186\fprq2 Cambria Math Baltic;}
{\f388\fbidi \froman\fcharset163\fprq2 Cambria Math (Vietnamese);}{\f422\fbidi \fswiss\fcharset0\fprq2 Tahoma{\*\falt Tahoma};}{\f421\fbidi \fswiss\fcharset204\fprq2 Tahoma Cyr{\*\falt Tahoma};}
{\f423\fbidi \fswiss\fcharset161\fprq2 Tahoma Greek{\*\falt Tahoma};}{\f424\fbidi \fswiss\fcharset162\fprq2 Tahoma Tur{\*\falt Tahoma};}{\f425\fbidi \fswiss\fcharset177\fprq2 Tahoma (Hebrew){\*\falt Tahoma};}
{\f426\fbidi \fswiss\fcharset178\fprq2 Tahoma (Arabic){\*\falt Tahoma};}{\f427\fbidi \fswiss\fcharset186\fprq2 Tahoma Baltic{\*\falt Tahoma};}{\f428\fbidi \fswiss\fcharset163\fprq2 Tahoma (Vietnamese){\*\falt Tahoma};}
{\f429\fbidi \fswiss\fcharset222\fprq2 Tahoma (Thai){\*\falt Tahoma};}{\f432\fbidi \fswiss\fcharset0\fprq2 Arial Narrow;}{\f431\fbidi \fswiss\fcharset204\fprq2 Arial Narrow Cyr;}{\f433\fbidi \fswiss\fcharset161\fprq2 Arial Narrow Greek;}
{\f434\fbidi \fswiss\fcharset162\fprq2 Arial Narrow Tur;}{\f437\fbidi \fswiss\fcharset186\fprq2 Arial Narrow Baltic;}{\flomajor\f31510\fbidi \froman\fcharset0\fprq2 Times New Roman{\*\falt Times New Roman};}
{\flomajor\f31509\fbidi \froman\fcharset204\fprq2 Times New Roman Cyr{\*\falt Times New Roman};}{\flomajor\f31511\fbidi \froman\fcharset161\fprq2 Times New Roman Greek{\*\falt Times New Roman};}
{\flomajor\f31512\fbidi \froman\fcharset162\fprq2 Times New Roman Tur{\*\falt Times New Roman};}{\flomajor\f31513\fbidi \froman\fcharset177\fprq2 Times New Roman (Hebrew){\*\falt Times New Roman};}
{\flomajor\f31514\fbidi \froman\fcharset178\fprq2 Times New Roman (Arabic){\*\falt Times New Roman};}{\flomajor\f31515\fbidi \froman\fcharset186\fprq2 Times New Roman Baltic{\*\falt Times New Roman};}
{\flomajor\f31516\fbidi \froman\fcharset163\fprq2 Times New Roman (Vietnamese){\*\falt Times New Roman};}{\fdbmajor\f31520\fbidi \froman\fcharset0\fprq2 Times New Roman{\*\falt Times New Roman};}
{\fdbmajor\f31519\fbidi \froman\fcharset204\fprq2 Times New Roman Cyr{\*\falt Times New Roman};}{\fdbmajor\f31521\fbidi \froman\fcharset161\fprq2 Times New Roman Greek{\*\falt Times New Roman};}
{\fdbmajor\f31522\fbidi \froman\fcharset162\fprq2 Times New Roman Tur{\*\falt Times New Roman};}{\fdbmajor\f31523\fbidi \froman\fcharset177\fprq2 Times New Roman (Hebrew){\*\falt Times New Roman};}
{\fdbmajor\f31524\fbidi \froman\fcharset178\fprq2 Times New Roman (Arabic){\*\falt Times New Roman};}{\fdbmajor\f31525\fbidi \froman\fcharset186\fprq2 Times New Roman Baltic{\*\falt Times New Roman};}
{\fdbmajor\f31526\fbidi \froman\fcharset163\fprq2 Times New Roman (Vietnamese){\*\falt Times New Roman};}{\fhimajor\f31530\fbidi \froman\fcharset0\fprq2 Cambria;}{\fhimajor\f31529\fbidi \froman\fcharset204\fprq2 Cambria Cyr;}
{\fhimajor\f31531\fbidi \froman\fcharset161\fprq2 Cambria Greek;}{\fhimajor\f31532\fbidi \froman\fcharset162\fprq2 Cambria Tur;}{\fhimajor\f31535\fbidi \froman\fcharset186\fprq2 Cambria Baltic;}
{\fhimajor\f31536\fbidi \froman\fcharset163\fprq2 Cambria (Vietnamese);}{\fbimajor\f31540\fbidi \froman\fcharset0\fprq2 Times New Roman{\*\falt Times New Roman};}
{\fbimajor\f31539\fbidi \froman\fcharset204\fprq2 Times New Roman Cyr{\*\falt Times New Roman};}{\fbimajor\f31541\fbidi \froman\fcharset161\fprq2 Times New Roman Greek{\*\falt Times New Roman};}
{\fbimajor\f31542\fbidi \froman\fcharset162\fprq2 Times New Roman Tur{\*\falt Times New Roman};}{\fbimajor\f31543\fbidi \froman\fcharset177\fprq2 Times New Roman (Hebrew){\*\falt Times New Roman};}
{\fbimajor\f31544\fbidi \froman\fcharset178\fprq2 Times New Roman (Arabic){\*\falt Times New Roman};}{\fbimajor\f31545\fbidi \froman\fcharset186\fprq2 Times New Roman Baltic{\*\falt Times New Roman};}
{\fbimajor\f31546\fbidi \froman\fcharset163\fprq2 Times New Roman (Vietnamese){\*\falt Times New Roman};}{\flominor\f31550\fbidi \froman\fcharset0\fprq2 Times New Roman{\*\falt Times New Roman};}
{\flominor\f31549\fbidi \froman\fcharset204\fprq2 Times New Roman Cyr{\*\falt Times New Roman};}{\flominor\f31551\fbidi \froman\fcharset161\fprq2 Times New Roman Greek{\*\falt Times New Roman};}
{\flominor\f31552\fbidi \froman\fcharset162\fprq2 Times New Roman Tur{\*\falt Times New Roman};}{\flominor\f31553\fbidi \froman\fcharset177\fprq2 Times New Roman (Hebrew){\*\falt Times New Roman};}
{\flominor\f31554\fbidi \froman\fcharset178\fprq2 Times New Roman (Arabic){\*\falt Times New Roman};}{\flominor\f31555\fbidi \froman\fcharset186\fprq2 Times New Roman Baltic{\*\falt Times New Roman};}
{\flominor\f31556\fbidi \froman\fcharset163\fprq2 Times New Roman (Vietnamese){\*\falt Times New Roman};}{\fdbminor\f31560\fbidi \froman\fcharset0\fprq2 Times New Roman{\*\falt Times New Roman};}
{\fdbminor\f31559\fbidi \froman\fcharset204\fprq2 Times New Roman Cyr{\*\falt Times New Roman};}{\fdbminor\f31561\fbidi \froman\fcharset161\fprq2 Times New Roman Greek{\*\falt Times New Roman};}
{\fdbminor\f31562\fbidi \froman\fcharset162\fprq2 Times New Roman Tur{\*\falt Times New Roman};}{\fdbminor\f31563\fbidi \froman\fcharset177\fprq2 Times New Roman (Hebrew){\*\falt Times New Roman};}
{\fdbminor\f31564\fbidi \froman\fcharset178\fprq2 Times New Roman (Arabic){\*\falt Times New Roman};}{\fdbminor\f31565\fbidi \froman\fcharset186\fprq2 Times New Roman Baltic{\*\falt Times New Roman};}
{\fdbminor\f31566\fbidi \froman\fcharset163\fprq2 Times New Roman (Vietnamese){\*\falt Times New Roman};}{\fhiminor\f31570\fbidi \fswiss\fcharset0\fprq2 Calibri;}{\fhiminor\f31569\fbidi \fswiss\fcharset204\fprq2 Calibri Cyr;}
{\fhiminor\f31571\fbidi \fswiss\fcharset161\fprq2 Calibri Greek;}{\fhiminor\f31572\fbidi \fswiss\fcharset162\fprq2 Calibri Tur;}{\fhiminor\f31575\fbidi \fswiss\fcharset186\fprq2 Calibri Baltic;}
{\fhiminor\f31576\fbidi \fswiss\fcharset163\fprq2 Calibri (Vietnamese);}{\fbiminor\f31580\fbidi \froman\fcharset0\fprq2 Times New Roman{\*\falt Times New Roman};}
{\fbiminor\f31579\fbidi \froman\fcharset204\fprq2 Times New Roman Cyr{\*\falt Times New Roman};}{\fbiminor\f31581\fbidi \froman\fcharset161\fprq2 Times New Roman Greek{\*\falt Times New Roman};}
{\fbiminor\f31582\fbidi \froman\fcharset162\fprq2 Times New Roman Tur{\*\falt Times New Roman};}{\fbiminor\f31583\fbidi \froman\fcharset177\fprq2 Times New Roman (Hebrew){\*\falt Times New Roman};}
{\fbiminor\f31584\fbidi \froman\fcharset178\fprq2 Times New Roman (Arabic){\*\falt Times New Roman};}{\fbiminor\f31585\fbidi \froman\fcharset186\fprq2 Times New Roman Baltic{\*\falt Times New Roman};}
{\fbiminor\f31586\fbidi \froman\fcharset163\fprq2 Times New Roman (Vietnamese){\*\falt Times New Roman};}}{\colortbl;\red0\green0\blue0;\red0\green0\blue255;\red0\green255\blue255;\red0\green255\blue0;\red255\green0\blue255;\red255\green0\blue0;
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}{\*\defchp \fs22 }{\*\defpap \ql \li0\ri0\sa200\sl276\slmult1\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 }\noqfpromote {\stylesheet{\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 
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\sbasedon0 \snext21 \styrsid8257923 Char Char Char Char Char Char,Char Char Char Char Char Char Char Char Char Char;}{\*\cs22 \additive \rtlch\fcs1 \af0\afs16 \ltrch\fcs0 \fs16 \sbasedon10 \ssemihidden \styrsid13898009 annotation reference;}{
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\sbasedon23 \snext23 \slink26 \ssemihidden \styrsid13898009 annotation subject;}{\*\cs26 \additive \rtlch\fcs1 \ab\af0\afs20 \ltrch\fcs0 \b\fs20\lang0\langfe1033\langfenp1033 \sbasedon24 \slink25 \slocked \ssemihidden P\'f8edm\'ect koment\'e1\'f8e Char;}{
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\trbrdrr\brdrs\brdrw10 \trbrdrh\brdrs\brdrw10 \trbrdrv\brdrs\brdrw10 
\trftsWidthB3\trpaddl108\trpaddr108\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind0\tblindtype3\tscellwidthfts0\tsvertalt\tsbrdrt\tsbrdrl\tsbrdrb\tsbrdrr\tsbrdrdgl\tsbrdrdgr\tsbrdrh\tsbrdrv 
\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs20\alang1025 \ltrch\fcs0 \fs20\lang1051\langfe1051\cgrid\langnp1051\langfenp1051 \sbasedon11 \snext29 \styrsid1195956 Table Grid;}}{\*\listtable
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\'01\u-3929 ?;}{\levelnumbers;}\f10\fbias0\hres0\chhres0 \fi-360\li2520\jclisttab\tx2520\lin2520 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67436545
\'01\u-3913 ?;}{\levelnumbers;}\f3\fbias0\hres0\chhres0 \fi-360\li3240\jclisttab\tx3240\lin3240 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67436547
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\'01\u-3929 ?;}{\levelnumbers;}\f10\fbias0\hres0\chhres0 \fi-360\li4680\jclisttab\tx4680\lin4680 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67436545
\'01\u-3913 ?;}{\levelnumbers;}\f3\fbias0\hres0\chhres0 \fi-360\li5400\jclisttab\tx5400\lin5400 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67436547
\'01o;}{\levelnumbers;}\f2\fbias0\hres0\chhres0 \fi-360\li6120\jclisttab\tx6120\lin6120 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67436549
\'01\u-3929 ?;}{\levelnumbers;}\f10\fbias0\hres0\chhres0 \fi-360\li6840\jclisttab\tx6840\lin6840 }{\listname ;}\listid972562040}{\list\listtemplateid788318340{\listlevel\levelnfc0\levelnfcn0\leveljc0\leveljcn0\levelfollow0\levelstartat10\levelspace0
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{\leveltext\'04\'00.\'01.;}{\levelnumbers\'01\'03;}\rtlch\fcs1 \af0 \ltrch\fcs0 \b\fbias0\hres0\chhres0 \fi-720\li720\jclisttab\tx720\lin720 }{\listlevel\levelnfc0\levelnfcn0\leveljc0\leveljcn0\levelfollow0\levelstartat1\levelspace0\levelindent0
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\levelstartat1\levelspace0\levelindent0{\leveltext\'12\'00.\'01.\'02.\'03.\'04.\'05.\'06.\'07.\'08.;}{\levelnumbers\'01\'03\'05\'07\'09\'0b\'0d\'0f\'11;}\rtlch\fcs1 \af0 \ltrch\fcs0 \b\fbias0\hres0\chhres0 \fi-1800\li1800\jclisttab\tx1800\lin1800 }
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\'01\u-3929 ?;}{\levelnumbers;}\f10\fbias0\hres0\chhres0 \fi-360\li2520\jclisttab\tx2520\lin2520 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67698689
\'01\u-3913 ?;}{\levelnumbers;}\f3\fbias0\hres0\chhres0 \fi-360\li3240\jclisttab\tx3240\lin3240 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67698691
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\'01\u-3929 ?;}{\levelnumbers;}\f10\fbias0\hres0\chhres0 \fi-360\li4680\jclisttab\tx4680\lin4680 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67698689
\'01\u-3913 ?;}{\levelnumbers;}\f3\fbias0\hres0\chhres0 \fi-360\li5400\jclisttab\tx5400\lin5400 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67698691
\'01o;}{\levelnumbers;}\f2\fbias0\hres0\chhres0 \fi-360\li6120\jclisttab\tx6120\lin6120 }{\listlevel\levelnfc23\levelnfcn23\leveljc0\leveljcn0\levelfollow0\levelstartat1\lvltentative\levelspace360\levelindent0{\leveltext\leveltemplateid67698693
\'01\u-3929 ?;}{\levelnumbers;}\f10\fbias0\hres0\chhres0 \fi-360\li6840\jclisttab\tx6840\lin6840 }{\listname ;}\listid1160314887}{\list\listtemplateid1730049510{\listlevel\levelnfc0\levelnfcn0\leveljc0\leveljcn0\levelfollow0\levelstartat1\levelspace360
\levelindent0{\leveltext\'02\'00.;}{\levelnumbers\'01;}\rtlch\fcs1 \af0 \ltrch\fcs0 \strike0\fbias0\hres0\chhres0 \fi-360\li360\jclisttab\tx360\lin360 }{\listlevel\levelnfc0\levelnfcn0\leveljc0\leveljcn0\levelfollow0\levelstartat1\levelspace0\levelindent0
{\leveltext\'04\'00.\'01.;}{\levelnumbers\'01\'03;}\rtlch\fcs1 \af0 \ltrch\fcs0 \b0\strike0\fbias0\hres0\chhres0 \fi-360\li360\jclisttab\tx360\lin360 }{\listlevel\levelnfc0\levelnfcn0\leveljc0\leveljcn0\levelfollow0\levelstartat1\levelspace0\levelindent0
{\leveltext\'06\'00.\'01.\'02.;}{\levelnumbers\'01\'03\'05;}\rtlch\fcs1 \af0 \ltrch\fcs0 \fbias0\hres0\chhres0 \fi-720\li720\jclisttab\tx720\lin720 }{\listlevel\levelnfc0\levelnfcn0\leveljc0\leveljcn0\levelfollow0\levelstartat1\levelspace0\levelindent0
{\leveltext\'08\'00.\'01.\'02.\'03.;}{\levelnumbers\'01\'03\'05\'07;}\rtlch\fcs1 \af0 \ltrch\fcs0 \fbias0\hres0\chhres0 \fi-720\li720\jclisttab\tx720\lin720 }{\listlevel\levelnfc0\levelnfcn0\leveljc0\leveljcn0\levelfollow0\levelstartat1\levelspace0
\levelindent0{\leveltext\'0a\'00.\'01.\'02.\'03.\'04.;}{\levelnumbers\'01\'03\'05\'07\'09;}\rtlch\fcs1 \af0 \ltrch\fcs0 \fbias0\hres0\chhres0 \fi-1080\li1080\jclisttab\tx1080\lin1080 }{\listlevel\levelnfc0\levelnfcn0\leveljc0\leveljcn0\levelfollow0
\levelstartat1\levelspace0\levelindent0{\leveltext\'0c\'00.\'01.\'02.\'03.\'04.\'05.;}{\levelnumbers\'01\'03\'05\'07\'09\'0b;}\rtlch\fcs1 \af0 \ltrch\fcs0 \fbias0\hres0\chhres0 \fi-1080\li1080\jclisttab\tx1080\lin1080 }{\listlevel\levelnfc0\levelnfcn0
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\rsid15091829\rsid15099274\rsid15139029\rsid15140802\rsid15163251\rsid15210844\rsid15231472\rsid15285141\rsid15293436\rsid15430209\rsid15473606\rsid15599908\rsid15608336\rsid15612565\rsid15619470\rsid15625699\rsid15736142\rsid15739240\rsid15806135
\rsid15875343\rsid15877727\rsid15931898\rsid15937616\rsid15940778\rsid15941981\rsid15942932\rsid16087677\rsid16205538\rsid16256495\rsid16272789\rsid16324378\rsid16341466\rsid16401842\rsid16404535\rsid16411968\rsid16597245\rsid16660755\rsid16661670}
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{\author Michaela Gajdo\'9aov\'e1}{\operator Mat\'fa\'9a Teke\'be}{\creatim\yr2009\mo5\dy29\hr12\min7}{\revtim\yr2012\mo1\dy6\hr20\min40}{\printim\yr2009\mo5\dy28\hr12\min53}{\version30}{\edmins25}{\nofpages14}{\nofwords5327}{\nofchars30365}
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C:\\Documents and Settings\\Branko Polak\\Application Data\\Microsoft\\Templates\\Normal.dot}\ltrpar \sectd \ltrsect\linex0\headery708\footery708\colsx708\endnhere\sectlinegrid360\sectdefaultcl\sectrsid215306\sftnbj {\*\pnseclvl1
\pnucrm\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl2\pnucltr\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl3\pndec\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl4\pnlcltr\pnstart1\pnindent720\pnhang {\pntxta )}}{\*\pnseclvl5
\pndec\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl6\pnlcltr\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl7\pnlcrm\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl8\pnlcltr\pnstart1\pnindent720\pnhang 
{\pntxtb (}{\pntxta )}}{\*\pnseclvl9\pnlcrm\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}\pard\plain \ltrpar\qc \li0\ri0\sl360\slmult1\widctlpar\wrapdefault\faauto\rin0\lin0\itap0\pararsid215306 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0\afs40 \ltrch\fcs0 \b\fs40\insrsid9791998\charrsid11145242 Metodick}{\rtlch\fcs1 \af0\afs40 \ltrch\fcs0 \b\fs40\insrsid12074838\charrsid11145242 \'e1}{\rtlch\fcs1 \af0\afs40 
\ltrch\fcs0 \b\fs40\insrsid9791998\charrsid11145242  }{\rtlch\fcs1 \af0\afs40 \ltrch\fcs0 \b\fs40\insrsid12074838\charrsid11145242 pom\'f4cka}{\rtlch\fcs1 \af0\afs40 \ltrch\fcs0 \b\fs40\insrsid215306\charrsid11145242 
\par }\pard \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\faauto\rin0\lin0\itap0\pararsid12584132 {\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\insrsid12584132\charrsid11145242 pre vykon\'e1vanie farmako-ekonomick\'e9ho rozboru lieku, 
\par medic\'ednsko-ekonomick\'e9ho rozboru zdravotn\'edckej pom\'f4cky a
\par medic\'ednsko-ekonomick\'e9ho rozboru dietetickej potraviny  
\par }\pard \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6518115\charrsid11145242 
\par 
\par {\listtext\pard\plain\ltrpar \rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\lang1051\langfe1033\langfenp1033\insrsid7562602\charrsid11145242 \hich\af0\dbch\af0\loch\f0 I.\tab}}\pard \ltrpar
\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls27\adjustright\rin0\lin720\itap0\pararsid16660755 {\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\insrsid7562602\charrsid11145242 \'daVOD}{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 
\b\fs28\insrsid16411968\charrsid11145242 
\par }\pard\plain \ltrpar\s17\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid7028021 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16660755\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12608782\charrsid11145242 Ci}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 e\'beom }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9510249\charrsid11145242 farmako-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242 ekonomick\'e9ho }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9510249\charrsid11145242 rozboru }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5132501\charrsid11145242 lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid468481\charrsid11145242 
, medic\'ednsko-ekonomick\'e9ho rozboru zdravotn\'edckej pom\'f4cky}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9510249\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5972966\charrsid11145242 a medic\'ednsko-ekonomick\'e9
ho rozboru dietetickej potraviny }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6518115\charrsid11145242 a}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid13329605\charrsid11145242 lebo inej technol\'f3gie (\'efalej len \'84farmako-ekonomick\'fd rozbor\'93) je }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  poskytn\'fa\'9d spo\'beahliv\'e9 inform\'e1cie, ktor\'e9 m\'f4\'9eu podpori\'9d rozhodovac\'ed proces, aby sa dosiahla efekt\'edvnos\'9d pri }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid6126161\charrsid11145242 alok\'e1cii}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid141623\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 zdrojov. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9510249\charrsid11145242 
Farmako-ekonomick\'fd}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9510249\charrsid11145242 rozbor }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 pom\'e1ha v\~
rozhodovacom procese v\~zmysle }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6126161\charrsid11145242 komplexnosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  inform\'e1ci\'ed, na z\'e1klade ktor\'fdch sa prij\'edmaj\'fa rozhodnutia}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6126161\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6126161\charrsid11145242 U}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242 mo\'9e\'f2uje t\'fdm, ktor\'ed prij\'edmaj\'fa rozhodnutia}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16341466\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  vych\'e1dza\'9d z\~ }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6126161\charrsid11145242 overen\'fdch poznatkov a }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 inform\'e1ci\'ed}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6126161\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242 a\~prispieva k\~efekt\'edvnemu rozde\'beovaniu zdrojov.
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6126161\charrsid11145242 \tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 T}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid14884038\charrsid11145242 \'e1to metodick\'e1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14884038\charrsid11145242 pom\'f4cka}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  poskytuj}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4002258\charrsid11145242 e}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  n\'e1vod pre v\'fdrobcov}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid4987217\charrsid11145242 , }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9791998\charrsid11145242 zad\'e1vate\'beov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  a}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4987217\charrsid11145242 lebo}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 \~poskytovate\'beov zdravotnej starostlivosti pripravuj\'facich }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9510249\charrsid11145242 farmako-ekonomick\'fd}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9510249\charrsid11145242 rozbor }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 v\~zdravotn\'edctve, aby si predkladan\'fdmi n\'e1vrhmi zabezpe\'e8ili finan\'e8n
\'e9 krytie za }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4987217\charrsid11145242 \~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 lieky}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4987217\charrsid11145242  a}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid13329605\charrsid11145242 \~in\'e9 technol\'f3gie}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  poskytovan\'e9 z}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8076990\charrsid11145242 \~}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242 verejn\'fdch}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8076990\charrsid11145242  zdrojov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  riaden\'fdch zdravotn\'fdmi pois\'9dov\'f2ami a\~Ministerstvom zdravotn
\'edctva Slovenskej republiky}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8076990\charrsid11145242  (\'efalej len \'84ministerstvo\'93)}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid4987217\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid930684\charrsid11145242 
\par }\pard \ltrpar\s17\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid930684 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4987217\charrsid11145242 C}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
ie\'beom }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14884038\charrsid11145242 metodickej pom\'f4cky }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 je }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4987217\charrsid11145242 transparentn\'e9 a}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  efekt\'edvne vyu\'9e\'edvanie }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4987217\charrsid11145242 dostupn\'fdch }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 zdrojov. }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9510249\charrsid11145242 Farmako-ekonomick\'fd rozbor }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 vych\'e1dza z\~porovnania n\'e1kladov a\~\'fa\'e8inkov dvoch alebo viacer\'fdch alternat\'ed
vnych met\'f3d lie\'e8by. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10894003\charrsid11145242 Farmako-e}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8076990\charrsid11145242 konomick\'fd}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8076990\charrsid11145242 rozbor}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10894003\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 umo\'9e\'f2uje definova\'9d, \'e8i dan}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid468481\charrsid11145242 \'e1 technol\'f3gia}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  poskytuje dodato\'e8n\'fd }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10894003\charrsid11145242 farmako-}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242 ekonomick\'fd pr\'ednos (vy\'9a\'9a\'ed ako }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid930684\charrsid11145242 pri existuj\'facich alternat\'edvach)}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16341466\charrsid11145242 dostato\'e8ne vysok\'fd na to, aby }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 opr\'e1v\'f2oval jeho }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16341466\charrsid11145242 s
\'fa\'e8asn\'e9 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 finan\'e8n\'e9 krytie alebo zmenu \'farovne aktu\'e1lneho krytia v\'fdda}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10772443\charrsid11145242 vk}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242 ov. 
\par }\pard \ltrpar\s17\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid16660755 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5058387\charrsid11145242 Postupy}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid468481\charrsid11145242 v\~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14884038\charrsid11145242 metodickej pom\'f4cke }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5058387\charrsid11145242 s
\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  navrhnut\'e9 tak, aby umo\'9enili z\'edskanie spo\'beahliv\'fdch, porovnate\'ben\'fdch a\~reprodukovate\'ben\'fdch v\'fdsledkov, ktor\'e9 podporia prij\'edmanie rozhodnut\'ed. }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 Ich cie\'beom je zadefinova\'9d jednotn\'fa metodiku, ktor\'e1 umo\'9en\'ed zainteresovan\'fdm subjektom \'9atandardn\'fdm sp\'f4sobom vypo\'e8\'edta\'9d, \'e8i liek}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid15625699\charrsid11145242  alebo }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid468481\charrsid11145242 in\'e1 technol\'f3gia}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15625699\charrsid11145242 , ktor\'e9 s\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid7299663\charrsid11145242  predmetom farmako-ekonomick\'e9ho}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15625699\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid15625699\charrsid11145242 , s\'fa alebo nie s\'fa n\'e1kladovo efekt\'edvne}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\delrsid7299663\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid7299663\charrsid11145242 O}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 dpor\'fa\'e8ania }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8717639\charrsid11145242 uveden\'e9}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  v}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14884038\charrsid11145242 \~tej}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4021436\charrsid11145242 to }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14884038\charrsid11145242 metodickej pom
\'f4cke }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 \'9apecificky stanovuj\'fa, ktor\'fa met\'f3du hodnotenia zvoli\'9d a\~tak maximalizuj\'fa mo\'9enos\'9d porovn\'e1vania tak\'fdchto hodnoten\'ed}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid15619470\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  ako aj v\'fdrazne zni\'9euj\'fa mo\'9enos\'9d vytv\'e1rania chybn\'fdch z\'e1verov. 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid468481\charrsid11145242 
\par 
\par }\pard \ltrpar\s17\qj \li0\ri0\pagebb\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8589239 {\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\insrsid6518115\charrsid11145242 II. }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 
\b\fs28\insrsid16660755\charrsid11145242 \tab }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\insrsid7562602\charrsid11145242 PRINC\'cdPY UPLATNEN\'c9 PRI PR\'cdPRAVE METODICK}{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\insrsid14884038\charrsid11145242 EJ}{
\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\insrsid7562602\charrsid11145242  }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\insrsid1800639\charrsid11145242 POM}{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\insrsid10749664\charrsid11145242 \'d4}{\rtlch\fcs1 
\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid14884038\charrsid11145242 CKY}{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\insrsid16411968\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8717639\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 
\par }\pard \ltrpar\s17\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15941981 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 M}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid1800639\charrsid11145242 etodick\'e1 pom\'f4cka }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10817498\charrsid11145242 upravuje }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 hlavn\'e9 ot\'e1zky, ktor\'e9 sa m\'f4\'9eu vyskytn\'fa\'9d
 pri vykon\'e1van\'ed }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5790265\charrsid11145242 farmako-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 ekonomick\'e9ho }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5790265\charrsid11145242 rozboru}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8717639\charrsid11145242 Uveden\'e9 postupy}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9791998\charrsid11145242 s\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8717639\charrsid11145242  odpor\'fa\'e8an\'e9 na z\'e1klade odborn\'fdch poznatkov.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid8717639\charrsid11145242 Z}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9791998\charrsid11145242 \'e1rove\'f2 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10817498\charrsid11145242 nevylu\'e8uj\'fa }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9791998\charrsid11145242 flexibilitu}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10817498\charrsid11145242  v pr\'edpade}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9791998\charrsid11145242 , ak s\'fa odch\'fdlky v\~porovnan\'ed s\~}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid1800639\charrsid11145242 metodickou pom\'f4ckou }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 od\'f4vodnen\'e9. 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 
\par M}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1800639\charrsid11145242 etodick\'e1 pom\'f4cka }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9791998\charrsid11145242 je}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  vytvoren}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid15941981\charrsid11145242 \'e1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  v\~s\'falade s\~najlep\'9aou praxou z\'edskanou z\~celosvetovo uzn\'e1vanej literat\'fary o}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid15941981\charrsid11145242 \~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5790265\charrsid11145242 farmako}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10817498\charrsid11145242 ekon\'f3mii }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
zdravotnej starostlivosti a\~z\~medzin\'e1rodn\'fdch smern\'edc. 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 
\par V}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 \'fdsledky }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6698993\charrsid11145242 farmako-ekonomick\'e9ho}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid468481\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid6698993\charrsid11145242 rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6698993\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9791998\charrsid11145242 poskyt}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12584132\charrsid11145242 uj\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  osob\'e1m prij\'edmaj\'facim rozhodnutia spo\'beahliv\'e9 a\~presn\'e9 inform\'e1cie, ktor\'e9 }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid6698993\charrsid11145242 minimalizuj\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  riziko rozhodnut\'ed prijat\'fdch na z\'e1klade neur\'e8it\'fdch alebo nespr\'e1vnych inform\'e1ci\'ed o}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid12539873\charrsid11145242 \~n\'e1kladovej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 efekt\'edvnosti }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12539873\charrsid11145242 liekov, zdravotn\'edckych pom\'f4cok}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9384594\charrsid11145242 , dietetick\'fdch potrav\'edn}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12539873\charrsid11145242  a\~in\'fdch technol\'f3gi\'ed}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . V
\'9aetky \'fadaje, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5007155\charrsid11145242 ich }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 zdroje a}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 \~}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242 anal\'fdza}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 /-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8717639\charrsid11145242 y}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }
{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11617864\charrsid11145242 maj\'fa by\'9d jasne uveden\'e9 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5007155\charrsid11145242 a}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1851990\charrsid11145242 \~}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid5007155\charrsid11145242 zdokumentovan\'e9}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1851990\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11617864\charrsid11145242 a\~m\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242 by\'9d od\'f4vodnen\'e1 relevantnos\'9d \'fadajov a\~pr\'edstupov pou\'9eit\'fdch pri hodnoten\'ed.
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 
\par H}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6698993\charrsid11145242 lavn\'fdm }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 cie\'beom }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1800639\charrsid11145242 metodickej pom\'f4cky }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242 je u\'beah\'e8i\'9d rozhodovac\'ed proces poskytnut\'edm kvalitn\'fdch a\~porovnate\'ben\'fdch }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5790265\charrsid11145242 farmako-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242 ekonomick\'fdch }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6698993\charrsid11145242 rozborov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1851990\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5790265\charrsid11145242  }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8076990\charrsid11145242 ako }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6698993\charrsid11145242 aj podklady pre }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8076990\charrsid11145242 transparentn\'e9}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid468481\charrsid11145242 , }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8076990\charrsid11145242 \~objekt\'edvne }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid468481\charrsid11145242 a\~overite\'ben\'e9 }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid8076990\charrsid11145242 rozhodovanie o\~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1851990\charrsid11145242 alok\'e1cii }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8076990\charrsid11145242 verejn\'fdch zdrojov}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid5790265\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5790265\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2311294\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid2311294 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2311294\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid215306\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid7299663\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\lang1051\langfe1033\langfenp1033\insrsid794727\charrsid11145242 \hich\af0\dbch\af0\loch\f0 III.\tab}}\pard \ltrpar
\s17\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls9\adjustright\rin0\lin720\itap0\pararsid15941981 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid794727\charrsid11145242 P}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 
\b\fs28\insrsid7562602\charrsid11145242 RAKTICK}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid6633488\charrsid11145242 \'c1}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid7562602\charrsid11145242  \'c8AS\'8d PRE VYKON\'c1
VANIE FARMAKO-EKONOMICK\'c9HO ROZBORU }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4417663\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4417663 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid16660755\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid215306\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid7299663\charrsid11145242 Ty}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid794727\charrsid11145242 p farmako-ekonomick\'e9ho rozboru}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 
\b\fs28\ul\insrsid4417663\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid16660755\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid215306\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \lang1051\langfe1033\langfenp1033\insrsid933935\charrsid11145242 \hich\af0\dbch\af0\loch\f0 3.1.\tab}}\pard \ltrpar
\s17\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls19\ilvl1\adjustright\rin0\lin720\itap0\pararsid12349245 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid933935\charrsid11145242 Sp\'f4sob farmako-ekonomick\'e9ho rozboru sa obvykle zvol\'ed z
\~troch typov anal\'fdz v\~z\'e1vislosti na charakteristike sledovan\'e9ho klinick\'e9ho probl\'e9mu: }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid933935\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15028107 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid15028107\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f10\lang1051\langfe1033\langfenp1033\insrsid933935\charrsid11145242 \loch\af10\dbch\af0\hich\f10 \'76\tab}}\pard \ltrpar\s17\qj \fi-360\li1080\ri0\widctlpar
\jclisttab\tx1080\wrapdefault\aspalpha\aspnum\faauto\ls24\adjustright\rin0\lin1080\itap0\pararsid15028107 {\rtlch\fcs1 \af0 \ltrch\fcs0 \ul\insrsid933935\charrsid11145242 anal\'fdza minimaliz\'e1cie n\'e1kladov}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid933935\charrsid11145242  (Cost-Minimization Analysis, CMA)}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16660755\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li1080\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin1080\itap0\pararsid16660755 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid535812\charrsid11145242 Tento druh anal\'fdzy je prijate\'ben\'fd len v\~pr\'ed
pade intervenci\'ed s\~rovnakou \'fa\'e8innos\'9dou.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid933935\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f10\lang1051\langfe1033\langfenp1033\insrsid933935\charrsid11145242 \loch\af10\dbch\af0\hich\f10 \'76\tab}}\pard \ltrpar\s17\qj \fi-360\li1080\ri0\widctlpar
\jclisttab\tx1080\wrapdefault\aspalpha\aspnum\faauto\ls24\adjustright\rin0\lin1080\itap0\pararsid15028107 {\rtlch\fcs1 \af0 \ltrch\fcs0 \ul\insrsid933935\charrsid11145242 anal\'fdza efekt\'edvnosti n\'e1kladov}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid933935\charrsid11145242  (Cost-Effectivness Analysis, CEA)}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16660755\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li1080\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin1080\itap0\pararsid16660755 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid535812\charrsid11145242 Tento druh anal\'fdzy je prijate\'ben\'fd v\~pr\'edpade intervenci
\'ed zameran\'fdch na rovnak\'e9 ochorenia a\~syndr\'f3my.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid933935\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f10\lang1051\langfe1033\langfenp1033\insrsid933935\charrsid11145242 \loch\af10\dbch\af0\hich\f10 \'76\tab}}\pard \ltrpar\s17\qj \fi-360\li1080\ri0\widctlpar
\jclisttab\tx1080\wrapdefault\aspalpha\aspnum\faauto\ls24\adjustright\rin0\lin1080\itap0\pararsid15028107 {\rtlch\fcs1 \af0 \ltrch\fcs0 \ul\insrsid933935\charrsid11145242 anal\'fdza\~u\'9eito\'e8nosti n\'e1kladov}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid10708026\charrsid11145242   (}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid933935\charrsid11145242 Cost-Utility Analysis, CUA) 
\par }\pard \ltrpar\s17\qj \li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid933935 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid933935\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid215306\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \lang1051\langfe1033\langfenp1033\insrsid4417663\charrsid11145242 \hich\af0\dbch\af0\loch\f0 3.2.\tab}}\pard \ltrpar
\s17\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls19\ilvl1\adjustright\rin0\lin720\itap0\pararsid12349245 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4417663\charrsid11145242 \'cfal\'9aie anal\'fdzy, ktor\'e9 s\'fa\'e8asn\'e1 farmakoekon
\'f3mia rozli\'9auje, av\'9aak ich pou\'9eitie sa neodpor\'fa\'e8a pri vypracovan\'ed farmako-ekonomick\'e9ho rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4417663\charrsid11145242  s\'fa:}
{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid4417663\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15028107 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid15028107\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f10\lang1051\langfe1033\langfenp1033\insrsid4417663\charrsid11145242 \loch\af10\dbch\af0\hich\f10 \'76\tab}}\pard \ltrpar\s17\qj \fi-360\li1080\ri0\widctlpar
\jclisttab\tx1080\wrapdefault\aspalpha\aspnum\faauto\ls25\adjustright\rin0\lin1080\itap0\pararsid15028107 {\rtlch\fcs1 \af0 \ltrch\fcs0 \ul\insrsid4417663\charrsid11145242 anal\'fdza }{\rtlch\fcs1 \af0 \ltrch\fcs0 \ul\insrsid14291480\charrsid11145242 n
\'e1kladov a pr\'ednosov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10708026\charrsid11145242  (}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4417663\charrsid11145242 Cost-benefit Analysis, CBA)}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10708026\charrsid11145242 ,}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4417663\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f10\lang1051\langfe1033\langfenp1033\insrsid4417663\charrsid11145242 \loch\af10\dbch\af0\hich\f10 \'76\tab}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \ul\insrsid4417663\charrsid11145242 \'9at\'fadia n
\'e1kladovosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4417663\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid933935\charrsid11145242 (Cost of I}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4417663\charrsid11145242 llness}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid933935\charrsid11145242 , COI}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4417663\charrsid11145242 )}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3543870\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4417663\charrsid11145242  
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f10\lang1051\langfe1033\langfenp1033\insrsid9709548\charrsid11145242 \loch\af10\dbch\af0\hich\f10 \'76\tab}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \ul\insrsid9709548\charrsid11145242 anal\'fdza }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \ul\insrsid3543870\charrsid11145242 rozpo\'e8tov\'e9ho vplyvu}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3543870\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15210844\charrsid11145242 (Budget Impact Analysis, BIA)}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4596013\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4417663\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid12649354 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid933935\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid16660755 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6835780\charrsid11145242 Tab. \'e8. 1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9709548\charrsid11145242 Stru\'e8n\'fd preh\'bead vyu\'9eitia jednotliv\'fdch typov anal\'fdz:
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15941981\charrsid11145242 
\par \ltrrow}\trowd \irow0\irowband0\ltrrow\ts11\trqc\trgaph70\trrh453\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvertalc\clbrdrt\brdrnone \clbrdrl
\brdrnone \clbrdrb\brdrnone \clbrdrr\brdrnone \cltxlrtb\clNoWrap\clftsWidth3\clwWidth8475\clshdrawnil \cellx8460\pard\plain \ltrpar\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 \rtlch\fcs1 
\af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \b\fs28\cf6\insrsid933935\charrsid11145242 Met\'f3dy farmako-ekonomick\'fdch anal\'fdz a ich vyu\'9eitie\cell }\pard \ltrpar
\ql \li0\ri0\sa200\sl276\slmult1\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \b\fs20\insrsid933935\charrsid11145242 \trowd \irow0\irowband0\ltrrow
\ts11\trqc\trgaph70\trrh453\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrnone \clbrdrr
\brdrnone \cltxlrtb\clNoWrap\clftsWidth3\clwWidth8475\clshdrawnil \cellx8460\row \ltrrow}\trowd \irow1\irowband1\ltrrow
\ts11\trqc\trgaph70\trrh1230\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvertalc\clbrdrt\brdrs\brdrw20 \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw20 \clbrdrr\brdrs\brdrw10 \clcbpat16\cltxlrtb\clftsWidth3\clwWidth1189\clcbpatraw16 \cellx1174\clvertalc\clbrdrt\brdrs\brdrw20 \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw20 \clbrdrr\brdrs\brdrw10 
\clcbpat16\cltxlrtb\clftsWidth3\clwWidth1900\clcbpatraw16 \cellx3074\clvertalc\clbrdrt\brdrs\brdrw20 \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw20 \clbrdrr\brdrs\brdrw10 \clcbpat16\cltxlrtb\clftsWidth3\clwWidth2326\clcbpatraw16 \cellx5400\clvertalc\clbrdrt
\brdrs\brdrw20 \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw20 \clbrdrr\brdrs\brdrw20 \clcbpat16\cltxlrtb\clftsWidth3\clwWidth3060\clcbpatraw16 \cellx8460\pard \ltrpar
\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 {\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 Met\'f3da\cell Sp\'f4soby merania n\'e1kladov\cell Sp\'f4soby merania v
\'fdnosov\cell V\'fdstupy\cell }\pard \ltrpar\ql \li0\ri0\sa200\sl276\slmult1\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\insrsid15210844\charrsid11145242 
\trowd \irow1\irowband1\ltrrow\ts11\trqc\trgaph70\trrh1230\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvertalc\clbrdrt\brdrs\brdrw20 \clbrdrl
\brdrs\brdrw20 \clbrdrb\brdrs\brdrw20 \clbrdrr\brdrs\brdrw10 \clcbpat16\cltxlrtb\clftsWidth3\clwWidth1189\clcbpatraw16 \cellx1174\clvertalc\clbrdrt\brdrs\brdrw20 \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw20 \clbrdrr\brdrs\brdrw10 
\clcbpat16\cltxlrtb\clftsWidth3\clwWidth1900\clcbpatraw16 \cellx3074\clvertalc\clbrdrt\brdrs\brdrw20 \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw20 \clbrdrr\brdrs\brdrw10 \clcbpat16\cltxlrtb\clftsWidth3\clwWidth2326\clcbpatraw16 \cellx5400\clvertalc\clbrdrt
\brdrs\brdrw20 \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw20 \clbrdrr\brdrs\brdrw20 \clcbpat16\cltxlrtb\clftsWidth3\clwWidth3060\clcbpatraw16 \cellx8460\row \ltrrow}\trowd \irow2\irowband2\ltrrow
\ts11\trqc\trgaph70\trrh645\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clNoWrap\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\pard \ltrpar\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 {\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 
\b\fs32\cf6\insrsid15210844\charrsid11145242 CMA\cell }{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 hodnotov\'e9 ukazovatele\cell \'9eiaden\cell }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 
\fs28\insrsid16660755\charrsid11145242 P}{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \fs28\insrsid15210844\charrsid11145242 orovnanie n\'e1kladov dvoch technol\'f3gi\'ed, ktor\'e9 maj\'fa identick\'fa \'fa\'e8innos\'9d}{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 
\fs28\insrsid16660755\charrsid11145242 
\par }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \fs28\insrsid15210844\charrsid11145242 (v praxi takmer nemo\'9en\'e9 n\'e1js\'9d tak\'e9to porovnanie)\cell }\pard \ltrpar\ql \li0\ri0\sa200\sl276\slmult1
\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\insrsid15210844\charrsid11145242 \trowd \irow2\irowband2\ltrrow
\ts11\trqc\trgaph70\trrh645\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clNoWrap\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\row \ltrrow}\trowd \irow3\irowband3\ltrrow
\ts11\trqc\trgaph70\trrh405\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\pard \ltrpar\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 {\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 
\b\fs32\cf6\insrsid15210844\charrsid11145242 \cell }{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 \cell \cell }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \fs28\insrsid15210844\charrsid11145242 \cell }\pard \ltrpar
\ql \li0\ri0\sa200\sl276\slmult1\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\insrsid15210844\charrsid11145242 \trowd \irow3\irowband3\ltrrow
\ts11\trqc\trgaph70\trrh405\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\row \ltrrow}\pard \ltrpar\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 {\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 
\b\fs32\cf6\insrsid15210844\charrsid11145242 \cell }{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 \cell \cell }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \fs28\insrsid15210844\charrsid11145242 \cell }\pard \ltrpar
\ql \li0\ri0\sa200\sl276\slmult1\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\insrsid15210844\charrsid11145242 \trowd \irow4\irowband4\ltrrow
\ts11\trqc\trgaph70\trrh405\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\row \ltrrow}\trowd \irow5\irowband5\ltrrow
\ts11\trqc\trgaph70\trrh1020\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clNoWrap\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\pard \ltrpar\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 {\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 
\b\fs32\cf6\insrsid15210844\charrsid11145242 CBA\cell }{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 hodnotov\'e9 ukazovatele\cell pe\'f2a\'9en\'e9 jednotky\cell }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 
\fs28\insrsid15210844\charrsid11145242 Vstupy a\~v\'fdstupy s\'fa vyjadren\'e9 v\~pe\'f2a\'9en\'fdch jednotk\'e1ch\cell }\pard \ltrpar\ql \li0\ri0\sa200\sl276\slmult1\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 
\af0\afs20 \ltrch\fcs0 \fs20\insrsid15210844\charrsid11145242 \trowd \irow5\irowband5\ltrrow
\ts11\trqc\trgaph70\trrh1020\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clNoWrap\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmgf\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\row \ltrrow}\trowd \irow6\irowband6\ltrrow
\ts11\trqc\trgaph70\trrh405\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\pard \ltrpar\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 {\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 
\b\fs32\cf6\insrsid15210844\charrsid11145242 \cell }{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 \cell \cell }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \fs28\insrsid15210844\charrsid11145242 \cell }\pard \ltrpar
\ql \li0\ri0\sa200\sl276\slmult1\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\insrsid15210844\charrsid11145242 \trowd \irow6\irowband6\ltrrow
\ts11\trqc\trgaph70\trrh405\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\row \ltrrow}\pard \ltrpar\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 {\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 
\b\fs32\cf6\insrsid15210844\charrsid11145242 \cell }{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 \cell \cell }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \fs28\insrsid15210844\charrsid11145242 \cell }\pard \ltrpar
\ql \li0\ri0\sa200\sl276\slmult1\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\insrsid15210844\charrsid11145242 \trowd \irow7\irowband7\ltrrow
\ts11\trqc\trgaph70\trrh405\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil 
\cellx3074\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvmrg\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw10 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw20 \cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\row \ltrrow}\trowd \irow8\irowband8\ltrrow
\ts11\trqc\trgaph70\trrh1125\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clNoWrap\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil \cellx3074
\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw20 
\cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\pard \ltrpar\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 {\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 
\b\fs32\cf6\insrsid15210844\charrsid11145242 CEA\cell }{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 hodnotov\'e9 ukazovatele\cell natur\'e1lne jednotky
\par napr. z\'edskan\'e9 roky \'9eivota\cell }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 \fs28\insrsid15210844\charrsid11145242 Cena/n\'e1klady za zachr\'e1nen\'fd \'9eivot, resp. klinick\'fa jednotku\cell }\pard \ltrpar\ql \li0\ri0\sa200\sl276\slmult1
\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 \fs20\insrsid15210844\charrsid11145242 \trowd \irow8\irowband8\ltrrow
\ts11\trqc\trgaph70\trrh1125\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb
\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clNoWrap\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil \cellx3074
\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw20 
\cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\row \ltrrow}\trowd \irow9\irowband9\lastrow \ltrrow
\ts11\trqc\trgaph70\trrh810\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw10 \cltxlrtb\clNoWrap\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil \cellx3074\clvertalc
\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw20 
\cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\pard \ltrpar\qc \li0\ri0\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\pararsid16660755 {\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 
\b\fs32\cf6\insrsid15210844\charrsid11145242 CUA\cell }{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 hodnotov\'e9 ukazovatele\cell U\'9eito\'e8nos\'9d
\par }{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid16660755\charrsid11145242 n}{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid15210844\charrsid11145242 apr. QALY, DALY\cell }{\rtlch\fcs1 \af0\afs28 \ltrch\fcs0 
\fs28\insrsid15210844\charrsid11145242 Vyjadruje potreby pacienta; cena/QALY\cell }\pard \ltrpar\ql \li0\ri0\sa200\sl276\slmult1\widctlpar\intbl\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0 {\rtlch\fcs1 \af0\afs20 \ltrch\fcs0 
\fs20\insrsid15210844\charrsid11145242 \trowd \irow9\irowband9\lastrow \ltrrow
\ts11\trqc\trgaph70\trrh810\trleft-15\trftsWidth3\trwWidth8475\trftsWidthB3\trftsWidthA3\trautofit1\trpaddl70\trpaddr70\trpaddfl3\trpaddft3\trpaddfb3\trpaddfr3\tblind55\tblindtype3 \clvertalc\clbrdrt\brdrnone \clbrdrl\brdrs\brdrw20 \clbrdrb\brdrs\brdrw10 
\clbrdrr\brdrs\brdrw10 \cltxlrtb\clNoWrap\clftsWidth3\clwWidth1189\clshdrawnil \cellx1174\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth1900\clshdrawnil \cellx3074\clvertalc
\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw10 \cltxlrtb\clftsWidth3\clwWidth2326\clshdrawnil \cellx5400\clvertalc\clbrdrt\brdrnone \clbrdrl\brdrnone \clbrdrb\brdrs\brdrw10 \clbrdrr\brdrs\brdrw20 
\cltxlrtb\clftsWidth3\clwWidth3060\clshdrawnil \cellx8460\row }\pard\plain \ltrpar\s17\qc \li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid933935 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9709548\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12649354 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid12259620\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \b\lang1051\langfe1033\langfenp1033\insrsid11755884\charrsid11145242 \hich\af0\dbch\af0\loch\f0 3.3.\tab}}\pard \ltrpar
\s17\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls19\ilvl1\adjustright\rin0\lin720\itap0\pararsid12349245 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid11755884\charrsid11145242 CMA}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid6633488\charrsid11145242 
\par }\pard \ltrpar\s17\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12349245 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11755884\charrsid11145242 Anal\'fdza minimaliz\'e1cie n\'e1kladov sa pou\'9eije, ak s\'fa
 celkov\'e9 klinick\'e9 v\'fdsledky (napr. \'fa\'e8innos\'9d)}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15210844\charrsid11145242  medzi porovn\'e1van\'fdmi lie\'e8bami }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11755884\charrsid11145242 rovnak\'e9
. Tento typ anal\'fdzy sa m\'e1 zvoli\'9d vtedy, ak spo\'beahliv\'e9 vedeck\'e9 d\'f4kazy (napr. primerane ve\'bek\'e1 randomizovan\'e1 klinick\'e1 \'9at\'fadia)}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid11755884\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid11755884\charrsid11145242 potvrdia, \'9ee pr\'ednosy a\~negat\'edva (napr. ne\'9eiaduce \'fa\'e8inky) liekov }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15210844\charrsid11145242 alebo in\'fdch technol\'f3gi\'ed }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid11755884\charrsid11145242 s\'fa rovnak\'e9. V\~takomto pr\'edpade sa anal\'fdza zameria na porovnanie n\'e1kladov a\~na identifik\'e1ciu lacnej\'9aej strat\'e9gie.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15210844\charrsid11145242  Tak
\'e1to skuto\'e8nos\'9d}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11755884\charrsid11145242  je mimoriadne zriedkav\'e1, \'e8o sa odr\'e1\'9ea aj na ve\'bemi m\'e1lo frekventovanom pou\'9e\'edvan\'ed uvedenej met\'f3dy}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid15210844\charrsid11145242 , ktor\'e1 sa rad\'ed medzi }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4596013\charrsid11145242 \'e8iastkov\'e9 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15210844\charrsid11145242 ekonomick\'e9 anal\'fdzy}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid11755884\charrsid11145242 .
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid11755884 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid11755884\charrsid11145242 
\par 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \b\lang1051\langfe1033\langfenp1033\insrsid11755884\charrsid11145242 \hich\af0\dbch\af0\loch\f0 3.4.\tab}}\pard \ltrpar
\s17\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls19\ilvl1\adjustright\rin0\lin720\itap0\pararsid12349245 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid11755884\charrsid11145242  CEA}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8935646\charrsid11145242 
\par }\pard \ltrpar\s17\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12349245 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8935646\charrsid11145242 Anal\'fdza efekt\'edvnosti n\'e1kladov sa pou\'9eije, ak sa }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 \'fa\'e8innos\'9d}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8935646\charrsid11145242  l\'ed\'9ai. T\'e1to anal\'fdza sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 pr\'edpadne m
\'f4\'9ee }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3300062\charrsid11145242 doplni\'9d anal\'fdzou u\'9eito\'e8nosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242  n\'e1kladov. Typ farmako-ekonomick\'e9ho rozboru z\'e1vis\'ed na miere zlep
\'9aenia zdravia vo vz\'9dahu k\~r\'f4znym terapeutick\'fdm postupom. Anal\'fdza efekt\'edvnosti n\'e1kladov meria klinick\'fa \'fa\'e8innos\'9d v\~prirodzen\'fdch jednotk\'e1ch (napr. fyziologick\'e9 parametre, \'e8as bez pr\'edznakov ochorenia, ved\'be
aj\'9aie \'fa\'e8inky, po\'e8et zachr\'e1nen\'fdch rokov \'9eivota a\~spokojnos\'9d pacienta). }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8935646\charrsid11145242 Pri hodnoten\'ed sa porovn\'e1vaj\'fa n\'e1klady vyjadren\'e9 v\~pe\'f2a\'9en\'fdch hodnot\'e1
ch s\~pr\'ednosmi poskytovanej zdravotnej starostlivosti vyjadrenej v\~nepe\'f2a\'9en\'fdch jednotk\'e1ch. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 V\~anal\'fdze efekt\'edvnosti n\'e1kladov sa \'e8oraz viac vyu\'9e\'ed
va meranie pre chorobu \'9apecifickej a\~nie z}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12460157\charrsid11145242 \~u\'9eito\'e8nosti v}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 ych\'e1dzaj\'facej kvality \'9eivota (QoL), ktor\'e1
 vyjadruje zlep\'9aenie zdravia pomocou sk\'f3re alebo klinicky d\'f4le\'9eit\'fdch minim\'e1lnych zmien. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865\charrsid11145242 Ako sa napr\'edklad }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7489364\charrsid11145242 v
\~onkol\'f3gii }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865\charrsid11145242 vyu\'9e\'edva }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7489364\charrsid11145242 Karnofsk\'e9ho sk\'f3re}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865\charrsid11145242 . }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8066914\charrsid11145242 
\par }\pard \ltrpar\s17\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid215306 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1195956\charrsid11145242 Anal\'fdzy}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid6633488\charrsid11145242  efekt\'edvnosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1195956\charrsid11145242  n\'e1kladov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6633488\charrsid11145242  m\'f4\'9eu stanovi\'9d prefe}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid4200341\charrsid11145242 rovan\'fa dominantn\'fa strat\'e9giu. Ak}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6633488\charrsid11145242  je \'fa\'e8innej\'9aia lie\'e8ba z\'e1rove\'f2 lacnej\'9aia m\'f4\'9ee by\'9d pova\'9eovan\'e1 za dominantn\'fa. }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4200341\charrsid11145242 V\~takom pr\'edpade sa bude nach\'e1dza\'9d v\~kvadrante }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6835780\charrsid11145242 III.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4200341\charrsid11145242  pod
\'bea obr\'e1zku \'e8.1.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865\charrsid11145242  a\~v\~praxi po celkovom }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6835780\charrsid11145242 zhodnoten\'ed rozboru }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid6366865\charrsid11145242 bude}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6835780\charrsid11145242  tak\'fdto liek}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9707881\charrsid11145242 alebo in
\'e1 technol\'f3gia uhr\'e1dzan\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865\charrsid11145242 z\~verejn\'e9ho zdravotn\'e9ho poistenia.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6633488\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865\charrsid11145242 V\~pr\'edpade, \'9ee sa liek }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9707881\charrsid11145242 alebo in\'e1 technol\'f3gia }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865\charrsid11145242 nach
\'e1dza v\~kvadrante I. znamen\'e1 to, \'9ee m\'e1 ni\'9e\'9a\'ed klinick\'fd \'fa\'e8inok a\~vy\'9a\'9aie n\'e1klady, preto nie je}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6835780\charrsid11145242  nikdy}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid6366865\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid947793\charrsid11145242 uhr\'e1dzan\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865\charrsid11145242 z\~verejn\'e9ho zdravotn\'e9ho poistenia. 
\par }\pard \ltrpar\s17\qj \fi360\li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid2118532 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7734052\charrsid11145242 
\par 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid215306 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532\charrsid11145242 Obr\'e1zok \'e8. 1: }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid12263868\charrsid11145242 Rovina/graf }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532\charrsid11145242 efekt\'edvnosti n\'e1kladov
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 
\par }\pard \ltrpar\s17\qj \fi-360\li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid215306 {\field\fldedit\fldlock{\*\fldinst {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532\charrsid11145242  SHAPE  \\* MERGEFORMAT }
}{\fldrslt {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1024\langfe1024\noproof\langfenp1051\insrsid11091767 
{\shpgrp{\*\shpinst\shpleft0\shptop0\shpright9000\shpbottom5760\shpfhdr0\shpbxcolumn\shpbxignore\shpbypara\shpbyignore\shpwr3\shpwrk0\shpfblwtxt0\shpz1\shplockanchor\shplid1026
{\sp{\sn groupLeft}{\sv 2520}}{\sp{\sn groupTop}{\sv 1080}}{\sp{\sn groupRight}{\sv 11520}}{\sp{\sn groupBottom}{\sv 6840}}{\sp{\sn fFlipH}{\sv 0}}{\sp{\sn fFlipV}{\sv 0}}{\sp{\sn fLockRotation}{\sv 0}}{\sp{\sn fLockAspectRatio}{\sv 1}}
{\sp{\sn fLockPosition}{\sv 0}}{\sp{\sn lidRegroup}{\sv 0}}{\sp{\sn posh}{\sv 0}}{\sp{\sn posrelh}{\sv 3}}{\sp{\sn posv}{\sv 0}}{\sp{\sn posrelv}{\sv 3}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fAllowOverlap}{\sv 1}}{\sp{\sn fBehindDocument}{\sv 0}}
{\sp{\sn dgmt}{\sv 0}}{\sp{\sn fPseudoInline}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLockPosition}{\sv 1}}{\sp{\sn fLockRotation}{\sv 1}}{\shp{\*\shpinst\shplid1027
{\sp{\sn relLeft}{\sv 2520}}{\sp{\sn relTop}{\sv 1080}}{\sp{\sn relRight}{\sv 11520}}{\sp{\sn relBottom}{\sv 6840}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 75}}{\sp{\sn fLockText}{\sv 1}}{\sp{\sn cxk}{\sv 0}}
{\sp{\sn fShadowOK}{\sv 1}}{\sp{\sn f3DOK}{\sv 1}}{\sp{\sn fLineOK}{\sv 1}}{\sp{\sn fFillOK}{\sv 1}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn fNoFillHitTest}{\sv 1}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fPreferRelativeResize}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1028{\sp{\sn relLeft}{\sv 6480}}{\sp{\sn relTop}{\sv 1620}}{\sp{\sn relRight}{\sv 6481}}{\sp{\sn relBottom}{\sv 6167}}{\sp{\sn fRelFlipH}{\sv 1}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}
{\shp{\*\shpinst\shplid1029{\sp{\sn relLeft}{\sv 3061}}{\sp{\sn relTop}{\sv 3960}}{\sp{\sn relRight}{\sv 10260}}{\sp{\sn relBottom}{\sv 3960}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}
{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1030{\sp{\sn relLeft}{\sv 6120}}{\sp{\sn relTop}{\sv 1260}}
{\sp{\sn relRight}{\sv 7019}}{\sp{\sn relBottom}{\sv 1980}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 65536}}{\sp{\sn hspNext}{\sv 1030}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}
{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar
\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af43 \ltrch\fcs0 
\f43\insrsid15091829 + \'c4C
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 
\par }}}}{\shp{\*\shpinst\shplid1031{\sp{\sn relLeft}{\sv 6120}}{\sp{\sn relTop}{\sv 6120}}{\sp{\sn relRight}{\sv 7019}}{\sp{\sn relBottom}{\sv 6840}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 131072}}{\sp{\sn hspNext}{\sv 1031}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af43 \ltrch\fcs0 \f43\insrsid15091829 - \'c4C
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 
\par }}}}{\shp{\*\shpinst\shplid1032{\sp{\sn relLeft}{\sv 10440}}{\sp{\sn relTop}{\sv 3600}}{\sp{\sn relRight}{\sv 11339}}{\sp{\sn relBottom}{\sv 4320}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 196608}}{\sp{\sn hspNext}{\sv 1032}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af43 \ltrch\fcs0 \f43\insrsid15091829 + \'c4E
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 
\par }}}}{\shp{\*\shpinst\shplid1033{\sp{\sn relLeft}{\sv 2520}}{\sp{\sn relTop}{\sv 3600}}{\sp{\sn relRight}{\sv 3419}}{\sp{\sn relBottom}{\sv 4320}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 262144}}{\sp{\sn hspNext}{\sv 1033}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af43 \ltrch\fcs0 \f43\insrsid15091829 - \'c4E
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 
\par }}}}{\shp{\*\shpinst\shplid1034{\sp{\sn relLeft}{\sv 3780}}{\sp{\sn relTop}{\sv 2340}}{\sp{\sn relRight}{\sv 9720}}{\sp{\sn relBottom}{\sv 5220}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 1}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}
{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineDashing}{\sv 6}}{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLine}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}
{\shp{\*\shpinst\shplid1035{\sp{\sn relLeft}{\sv 7920}}{\sp{\sn relTop}{\sv 1440}}{\sp{\sn relRight}{\sv 9180}}{\sp{\sn relBottom}{\sv 2520}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 327680}}
{\sp{\sn hspNext}{\sv 1035}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar
\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 Pra}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 h}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 ov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 \'e9}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532  hodnot}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 
y intervalu}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 
\par }}}}{\shp{\*\shpinst\shplid1036{\sp{\sn relLeft}{\sv 4680}}{\sp{\sn relTop}{\sv 1440}}{\sp{\sn relRight}{\sv 8100}}{\sp{\sn relBottom}{\sv 6480}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 1}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}
{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineDashing}{\sv 6}}{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLine}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}
{\shp{\*\shpinst\shplid1037{\sp{\sn relLeft}{\sv 7560}}{\sp{\sn relTop}{\sv 1080}}{\sp{\sn relRight}{\sv 8100}}{\sp{\sn relBottom}{\sv 1620}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 393216}}
{\sp{\sn hspNext}{\sv 1037}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar
\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 
{\field{\*\fldinst SYMBOL 108 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 2
\par }}}}{\shp{\*\shpinst\shplid1038{\sp{\sn relLeft}{\sv 9180}}{\sp{\sn relTop}{\sv 1980}}{\sp{\sn relRight}{\sv 10079}}{\sp{\sn relBottom}{\sv 2700}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 458752}}{\sp{\sn hspNext}{\sv 1038}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 {\field{\*\fldinst SYMBOL 108 \\f "Symbol" \\s 12}{\fldrslt\f3\fs24}}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 1
\par }}}}{\shp{\*\shpinst\shplid1039{\sp{\sn relLeft}{\sv 10440}}{\sp{\sn relTop}{\sv 5040}}{\sp{\sn relRight}{\sv 11520}}{\sp{\sn relBottom}{\sv 6840}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 524288}}{\sp{\sn hspNext}{\sv 1039}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865 III.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12263868  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 
\par }}}}{\shp{\*\shpinst\shplid1040{\sp{\sn relLeft}{\sv 2700}}{\sp{\sn relTop}{\sv 5400}}{\sp{\sn relRight}{\sv 3599}}{\sp{\sn relBottom}{\sv 6120}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 589824}}{\sp{\sn hspNext}{\sv 1040}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865 IV:}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 
\par }}}}{\shp{\*\shpinst\shplid1041{\sp{\sn relLeft}{\sv 2700}}{\sp{\sn relTop}{\sv 1620}}{\sp{\sn relRight}{\sv 3599}}{\sp{\sn relBottom}{\sv 2340}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 655360}}{\sp{\sn hspNext}{\sv 1041}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865 I.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 
\par }}}}{\shp{\*\shpinst\shplid1042{\sp{\sn relLeft}{\sv 10440}}{\sp{\sn relTop}{\sv 1620}}{\sp{\sn relRight}{\sv 11339}}{\sp{\sn relBottom}{\sv 2340}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 720896}}{\sp{\sn hspNext}{\sv 1042}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6366865 II.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 
\par }}}}{\shp{\*\shpinst\shplid1043{\sp{\sn relLeft}{\sv 7560}}{\sp{\sn relTop}{\sv 4680}}{\sp{\sn relRight}{\sv 9900}}{\sp{\sn relBottom}{\sv 5760}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 786432}}{\sp{\sn hspNext}{\sv 1043}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 Dominantn\'fd segment
\par }}}}{\shp{\*\shpinst\shplid1044{\sp{\sn relLeft}{\sv 3420}}{\sp{\sn relTop}{\sv 2160}}{\sp{\sn relRight}{\sv 5760}}{\sp{\sn relBottom}{\sv 3240}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 851968}}{\sp{\sn hspNext}{\sv 1044}}{\sp{\sn fRecolorFillAsPicture}{\sv 0}}{\sp{\sn fUseShapeAnchor}{\sv 0}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12263868 Dominovan\'fd}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8662863  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1033\langfe1033\langnp1033\insrsid12263868 /}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12263868 neefekt\'edvny segment
\par }}}}}{\shprslt{\*\do\dobxcolumn\dobypara\dodhgt8193\dpgroup\dpcount19\dpx0\dpy0\dpxsize9000\dpysize5760\dppolygon\dppolycount4\dpptx0\dppty0\dpptx0\dppty5760\dpptx9000\dppty5760\dpptx9000\dppty0\dpx0\dpy0\dpxsize9000\dpysize5760
\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat0\dplinehollow\dpline\dpptx1\dppty0\dpptx0\dppty4547\dpx3960\dpy540\dpxsize1\dpysize4547\dplinew15\dplinecor0\dplinecog0\dplinecob0
\dpline\dpptx0\dppty0\dpptx7199\dppty0\dpx541\dpy2880\dpxsize7199\dpysize0\dplinew15\dplinecor0\dplinecog0\dplinecob0\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar
\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af43 \ltrch\fcs0 
\f43\insrsid15091829 + \'c4C
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 
\par }}\dpx3600\dpy180\dpxsize899\dpysize720\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinehollow\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar
\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af43 \ltrch\fcs0 
\f43\insrsid15091829 - \'c4C
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15091829 
\par }}\dpx3600\dpy5040\dpxsize899\dpysize720\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinehollow\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar
\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af43 \ltrch\fcs0 
\f43\insrsid15091829 + \'c4E
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 
\par }}\dpx7920\dpy2520\dpxsize899\dpysize720\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinehollow\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar
\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12263868 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af43 \ltrch\fcs0 
\f43\insrsid15091829 - \'c4E
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2118532 
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\ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242 nosti }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 n\'e1kladov }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242 je }{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 zalo\'9een\'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  na }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 meran\'ed}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 pr\'ednosu}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\fs24\insrsid1512948\charrsid11145242 jednotliv\'fdch}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 terapeutick\'fdch}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 alternat\'edv}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  pomocou tzv. o\~kvalitu }{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 upraven\'fdch}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  rokov }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 \'9eivota}{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  (QALYs}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid9131336\charrsid11145242 , Quality}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid16087677\charrsid11145242 -}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \fs24\insrsid9131336\charrsid11145242 Adjusted Life Years}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242 ). Tieto }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 upravuj\'fa}{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 pred\'e5\'9eenie}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 \'9eivota}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242 , }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 sp\'f4soben\'e9}{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242  danou terapeutickou }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 alternat\'edvou}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242 
, kvalitou, v\~ktorom ho pacient }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid1512948\charrsid11145242 pre\'9eije}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12460157\charrsid11145242 . }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\fs24\insrsid1512948\charrsid11145242 
\par }\pard \ltrpar\s23\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid215306 {\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 Napr\'edklad}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\i\fs24\insrsid12460157\charrsid11145242  \endash  ak }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 dan\'fd}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  liek }{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 pred\'e5\'9ei}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 \'9eivot}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  pacienta s\~}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 karcin\'f3}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12847865\charrsid11145242 mom o\~5 rokov}{
\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242  a\~pacient poklad\'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 
\'9eivot}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  s\~}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 t\'fdmto}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242 
 druhom }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 karcin\'f3mu}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  za len }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\i\fs24\insrsid1512948\charrsid11145242 polovi\'e8ne}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 kvalitn\'fd}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid7734052\charrsid11145242 (0,5) }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242 oproti }{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 pln\'e9mu}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  zdraviu}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid5467164\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \i\fs24\insrsid7734052\charrsid11145242 (1)}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242 , }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 met\'f3da}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 predpoklad\'e1}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242 , }{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 \'9ee}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  pacient }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 v\'efaka}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 lie\'e8be}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 z\'edskal}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  5 x 0,5 = 2,5 o\~kvalitu }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 upraven\'fdch
}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242  rokov }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid1512948\charrsid11145242 \'9eivota}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12460157\charrsid11145242 
 (QALYs)}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid15028107\charrsid11145242 .}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid12259620\charrsid11145242 
\par }\pard \ltrpar\s23\ql \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid12259620 {\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid12259620\charrsid11145242 
\par }\pard \ltrpar\s23\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid215306 {\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid7299663\charrsid11145242 Odpor\'fa\'e8a sa, aby }{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \fs24\insrsid3101871\charrsid11145242 sa }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid7299663\charrsid11145242 anal\'fdza efekt\'edvnosti n\'e1kladov doplnila anal\'fdzou }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\fs24\insrsid4596013\charrsid11145242 u\'9eito\'e8nosti}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid215306\charrsid11145242  n\'e1kladov}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid7299663\charrsid11145242  v\'9edy}{\rtlch\fcs1 \af0\afs24 
\ltrch\fcs0 \fs24\insrsid215306\charrsid11145242 ,}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid7299663\charrsid11145242  ke\'ef s\'fa k\~dispoz\'edcii alebo sa daj\'fa z\'edska\'9d vhodn\'e9 \'fadaje.}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\fs24\insrsid215306\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid5467164\charrsid11145242 
\par }\pard \ltrpar\s23\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid5467164 {\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid7299663\charrsid11145242 Napr\'edklad anal\'fdza, ktor\'e1 hodnot\'ed zmeny v\~o\'e8
ak\'e1vanej d\'e5\'9eke \'9eivota sa m\'f4\'9ee doplni\'9d }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid4915976\charrsid11145242 anal\'fdzou }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid7299663\charrsid11145242 QALY (ak s\'fa }{\rtlch\fcs1 
\af0\afs24 \ltrch\fcs0 \i\fs24\insrsid8454267\charrsid11145242 hodnoty }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \i\fs24\insrsid7299663\charrsid11145242 zn\'e1me z\~prim\'e1rnej \'9at\'fadie alebo z\~literat\'fary).}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\fs24\insrsid7299663\charrsid11145242  }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid214835\charrsid11145242 
\par }\pard \ltrpar\s23\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid214835 {\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid5114767\charrsid11145242 Existuje na to }{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 
\fs24\insrsid7299663\charrsid11145242 nieko\'beko d\'f4}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid9131336\charrsid11145242 vodov}{\rtlch\fcs1 \af0\afs24 \ltrch\fcs0 \fs24\insrsid7299663\charrsid11145242 :}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid7299663\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid7299663\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}}\pard\plain \ltrpar
\s17\qj \fi-360\li540\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls3\adjustright\rin0\lin540\itap0\pararsid215306 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid7299663\charrsid11145242 V\'fdpo\'e8ty QALY ber\'fa okrem pre\'9e\'edvania do \'favahy aj }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12153090\charrsid11145242 kvalitu \'9eivota, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 a\~
tak reflektuj\'fa oba k\'be\'fa\'e8ov\'e9 ro}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9131336\charrsid11145242 zmery d\'f4le\'9eit\'e9 pre jednotlivcov, teda v\~akej kvalite pre\'9eije pacient viac rokov.}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid7299663\charrsid11145242  
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid7299663\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}V\'fdpo\'e8ty QALY umo\'9e\'f2uj\'fa porovnate\'benos\'9d \'fadajov o\~efekt\'ed
vnosti n\'e1kladov medzi jednotliv\'fdmi lie\'e8bami uplat\'f2ovan\'fdmi pre r\'f4zne ciele (ako to je pri r\'f4znych ochoreniach v\~r\'f4znych skupin\'e1ch pacientov). T\'fdmto sa m\'f4\'9ee podpori\'9d n\'e1kladovo efekt\'edvne rozde\'beovanie zdrojov v
\~r\'e1mci cel\'e9ho syst\'e9mu zdravotnej starostlivosti. 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid7299663\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}V\'fdpo\'e8ty QALY vo\~farmako-ekonomick\'fdch rozboroch v\~zdravotn\'edctve m\'f4\'9e
u prispie\'9d k\~stanoveniu n\'e1kladov\'e9ho prahu (intervalu), ktor\'fd odr\'e1\'9ea schopnos\'9d krajiny plati\'9d za dodato\'e8n\'e9 pr\'ednosy vyjadren\'e9 v\~QALY, \'e8\'edm sa podpor\'ed jasn\'e9 stanovenie prior\'edt pri rozhodovan\'ed o\~rozdelen
\'ed zdrojov. 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid7299663 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 
\par }\pard \ltrpar\s17\qj \fi540\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid215306 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9131336\charrsid11145242 Pri anal\'fdzach u\'9eito\'e8nost}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid7299663\charrsid11145242 i n\'e1kladov sa zlep\'9aenie zdravia \'9atandardne vyjadruje v\~QALY. QALY ako jednotka merania pr\'ednosu pre zdravie kombinuje zlep\'9aenie zdravia, ktor\'e9 sa odr\'e1\'9ea v\~o\'e8ak\'e1vanej d\'e5\'9eke \'9eivota a\~
v\~kvalite \'9eivota (vych\'e1dzaj\'facej z\~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12480286\charrsid11145242 u\'9eito\'e8nosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 ). Pre meranie zdravotn\'e9ho stavu sa uprednost\'f2uje odvodi
\'9d v\'fdpo\'e8ty QALY z\~pou\'9eitia na }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12782070\charrsid11145242 u\'9eito\'e8nosti }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 zalo\'9een\'fdch so zdrav\'edm s\'favisiacich dotazn\'ed
kov QoL, pre ktor\'e9 sa preferen\'e8n\'e9 hodnoty zistili zo v\'9aeobecn\'fdch popula\'e8n\'fdch prieskumov. Medzin\'e1rodne odpor\'fa\'e8an\'e9 dotazn\'edky zah\'e0\'f2aj\'fa EQ-5D, Health Utilities Index, Quality of Well-Being Scale. Tieto dotazn\'ed
ky meraj\'fa so zdrav\'edm s\'favisiacu kvalitu \'9eivota vo viacer\'fdch dimenzi\'e1ch. Ka\'9ed\'fd mo\'9en\'fd zdravotn\'fd stav klasifikovan\'fd dotazn\'edkom sa sp\'e1ja s\~\'farov\'f2ou }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid12782070\charrsid11145242 u\'9eito\'e8nosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 . Tieto \'farovne }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12782070\charrsid11145242 u\'9eito\'e8nosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid7299663\charrsid11145242  odr\'e1\'9eaj\'fa soci\'e1lne preferencie, ktor\'e9 sa zis\'9duj\'fa pomocou v\'9aeobecn\'fdch popula\'e8n\'fdch prieskumov pou\'9eit\'edm jednej z\~dostupn\'fdch priamych met\'f3d merania }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid12782070\charrsid11145242 u\'9eito\'e8nosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242  ako s\'fa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14492274\charrsid11145242 vizu\'e1lna analogick\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid7299663\charrsid11145242 \'9ak\'e1la}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10828828\charrsid11145242  (VAS \endash  visual analog scale)}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 , }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid4473479\charrsid11145242 met\'f3da \'e8asov\'e9ho kompromisu}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2844473\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 (}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid7016032\charrsid11145242 TTO - }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 time trade-off) a\~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14492274\charrsid11145242 \'9atandardn\'e1 lot\'e9ria}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid7016032\charrsid11145242  (SG \endash  standard gamble)}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 . V\~pr\'edpade }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12782070\charrsid11145242 liekov alebo in\'fdch technol\'f3gi\'ed }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 zameran\'fdch na ochorenia, pre ktor\'e9 zvy\'e8ajn\'e9 dotazn\'edky QoL nie dos\'9d citlivo odr\'e1\'9eaj\'fa zmeny v\~zdravotnom stave pacientov, je mo\'9en\'fdm variantom z\'edskanie hodn
\'f4t }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12782070\charrsid11145242 u\'9eito\'e8nosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242  od pacientov pomocou priamych met\'f3d merania }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid12782070\charrsid11145242 u\'9eito\'e8nosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12782070\delrsid12782070\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242 (hodno}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16256495\charrsid11145242 tiaca \'9ak\'e1la typu time trade-off}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7299663\charrsid11145242  alebo standard gamble). V\~pr\'edpade prisp\'f4sobovania zahrani\'e8n\'fdch \'9at\'fadi\'ed na slovensk\'e9
 pomery sa pop\'ed\'9ae met\'f3da v\'fdpo\'e8tu QALY pou\'9eit\'e1 v\~p\'f4vodnej \'9at\'fadii. 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid7299663\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid215306\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid3884484\charrsid11145242 V}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid15940778\charrsid11145242 \'fdstup}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 
\b\fs28\ul\insrsid3884484\charrsid11145242 y a}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid15940778\charrsid11145242  }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid215306\charrsid11145242 typy ek}{\rtlch\fcs1 \ab\af0\afs28 
\ltrch\fcs0 \b\fs28\ul\insrsid3884484\charrsid11145242 onomick\'e9ho hodnotenia}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\ul\insrsid1512948\charrsid11145242 
\par }\pard \ltrpar\s17\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 {\field\fldedit\fldlock{\*\fldinst {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid8747169\charrsid11145242  SHAPE  \\* MERGEFORMAT }
}{\fldrslt {\rtlch\fcs1 \af0 \ltrch\fcs0 \lang1024\langfe1024\noproof\langfenp1051\insrsid11091767 
{\shpgrp{\*\shpinst\shpleft0\shptop0\shpright8280\shpbottom5940\shpfhdr0\shpbxcolumn\shpbxignore\shpbypara\shpbyignore\shpwr3\shpwrk0\shpfblwtxt0\shpz0\shplockanchor\shplid1046
{\sp{\sn groupLeft}{\sv 2362}}{\sp{\sn groupTop}{\sv 7800}}{\sp{\sn groupRight}{\sv 9562}}{\sp{\sn groupBottom}{\sv 13080}}{\sp{\sn fFlipH}{\sv 0}}{\sp{\sn fFlipV}{\sv 0}}{\sp{\sn fLockRotation}{\sv 0}}{\sp{\sn fLockAspectRatio}{\sv 1}}
{\sp{\sn fLockPosition}{\sv 0}}{\sp{\sn lidRegroup}{\sv 0}}{\sp{\sn posh}{\sv 0}}{\sp{\sn posrelh}{\sv 3}}{\sp{\sn posv}{\sv 0}}{\sp{\sn posrelv}{\sv 3}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fAllowOverlap}{\sv 1}}{\sp{\sn fBehindDocument}{\sv 0}}
{\sp{\sn dgmt}{\sv 0}}{\sp{\sn fPseudoInline}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLockPosition}{\sv 1}}{\sp{\sn fLockRotation}{\sv 1}}{\shp{\*\shpinst\shplid1047
{\sp{\sn relLeft}{\sv 2362}}{\sp{\sn relTop}{\sv 7800}}{\sp{\sn relRight}{\sv 9562}}{\sp{\sn relBottom}{\sv 13080}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 75}}{\sp{\sn fLockText}{\sv 1}}{\sp{\sn cxk}{\sv 0}}
{\sp{\sn fShadowOK}{\sv 1}}{\sp{\sn f3DOK}{\sv 1}}{\sp{\sn fLineOK}{\sv 1}}{\sp{\sn fFillOK}{\sv 1}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn fNoFillHitTest}{\sv 1}}{\sp{\sn fLine}{\sv 0}}{\sp{\sn fPreferRelativeResize}{\sv 0}}{\sp{\sn fLayoutInCell}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1048{\sp{\sn relLeft}{\sv 4866}}{\sp{\sn relTop}{\sv 8280}}{\sp{\sn relRight}{\sv 6745}}{\sp{\sn relBottom}{\sv 8760}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 983040}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 Typ hodnotenia
\par }}}}{\shp{\*\shpinst\shplid1049{\sp{\sn relLeft}{\sv 3458}}{\sp{\sn relTop}{\sv 8600}}{\sp{\sn relRight}{\sv 4866}}{\sp{\sn relBottom}{\sv 9400}}{\sp{\sn fRelFlipH}{\sv 1}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}
{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}
{\shp{\*\shpinst\shplid1050{\sp{\sn relLeft}{\sv 6745}}{\sp{\sn relTop}{\sv 8600}}{\sp{\sn relRight}{\sv 8153}}{\sp{\sn relBottom}{\sv 9400}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}
{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}
{\shp{\*\shpinst\shplid1051{\sp{\sn relLeft}{\sv 2519}}{\sp{\sn relTop}{\sv 9560}}{\sp{\sn relRight}{\sv 4397}}{\sp{\sn relBottom}{\sv 10040}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 1048576}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid8747169\charrsid8747169 Cost-effectivness
\par }}}}{\shp{\*\shpinst\shplid1052{\sp{\sn relLeft}{\sv 3301}}{\sp{\sn relTop}{\sv 10200}}{\sp{\sn relRight}{\sv 3303}}{\sp{\sn relBottom}{\sv 10520}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}
{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1053{\sp{\sn relLeft}{\sv 2519}}{\sp{\sn relTop}{\sv 10680}}
{\sp{\sn relRight}{\sv 4396}}{\sp{\sn relBottom}{\sv 11160}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 1114112}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar 
\pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 Zdravotn\'fd stav
\par }}}}{\shp{\*\shpinst\shplid1054{\sp{\sn relLeft}{\sv 3301}}{\sp{\sn relTop}{\sv 11320}}{\sp{\sn relRight}{\sv 3301}}{\sp{\sn relBottom}{\sv 11640}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}
{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1055{\sp{\sn relLeft}{\sv 4866}}{\sp{\sn relTop}{\sv 10275}}
{\sp{\sn relRight}{\sv 6745}}{\sp{\sn relBottom}{\sv 10840}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 1179648}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar 
\pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 Meranie v\'fdstupov
\par }}}}{\shp{\*\shpinst\shplid1056{\sp{\sn relLeft}{\sv 8153}}{\sp{\sn relTop}{\sv 10200}}{\sp{\sn relRight}{\sv 8154}}{\sp{\sn relBottom}{\sv 10520}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}
{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1057{\sp{\sn relLeft}{\sv 7371}}{\sp{\sn relTop}{\sv 9560}}
{\sp{\sn relRight}{\sv 9092}}{\sp{\sn relBottom}{\sv 10040}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 1245184}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar 
\pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 Cost-utility
\par }}}}{\shp{\*\shpinst\shplid1058{\sp{\sn relLeft}{\sv 7371}}{\sp{\sn relTop}{\sv 10680}}{\sp{\sn relRight}{\sv 9249}}{\sp{\sn relBottom}{\sv 11160}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 1310720}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 QALY
\par }}}}{\shp{\*\shpinst\shplid1059{\sp{\sn relLeft}{\sv 5179}}{\sp{\sn relTop}{\sv 11320}}{\sp{\sn relRight}{\sv 6432}}{\sp{\sn relBottom}{\sv 11800}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 1376256}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 EQ-5D
\par }}}}{\shp{\*\shpinst\shplid1060{\sp{\sn relLeft}{\sv 5336}}{\sp{\sn relTop}{\sv 12035}}{\sp{\sn relRight}{\sv 6275}}{\sp{\sn relBottom}{\sv 12835}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 1441792}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 HUI
\par 15-D
\par }}}}{\shp{\*\shpinst\shplid1061{\sp{\sn relLeft}{\sv 5805}}{\sp{\sn relTop}{\sv 10840}}{\sp{\sn relRight}{\sv 5806}}{\sp{\sn relBottom}{\sv 11320}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}
{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1062{\sp{\sn relLeft}{\sv 8153}}{\sp{\sn relTop}{\sv 11320}}
{\sp{\sn relRight}{\sv 8154}}{\sp{\sn relBottom}{\sv 11640}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}
{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1063{\sp{\sn relLeft}{\sv 4397}}{\sp{\sn relTop}{\sv 11480}}
{\sp{\sn relRight}{\sv 5179}}{\sp{\sn relBottom}{\sv 11960}}{\sp{\sn fRelFlipH}{\sv 1}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}
{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1064{\sp{\sn relLeft}{\sv 4397}}{\sp{\sn relTop}{\sv 12120}}
{\sp{\sn relRight}{\sv 5336}}{\sp{\sn relBottom}{\sv 12600}}{\sp{\sn fRelFlipH}{\sv 1}}{\sp{\sn fRelFlipV}{\sv 1}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}
{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1065{\sp{\sn relLeft}{\sv 6432}}{\sp{\sn relTop}{\sv 11480}}
{\sp{\sn relRight}{\sv 7371}}{\sp{\sn relBottom}{\sv 11960}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}
{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1066{\sp{\sn relLeft}{\sv 6275}}{\sp{\sn relTop}{\sv 12120}}
{\sp{\sn relRight}{\sv 7371}}{\sp{\sn relBottom}{\sv 12600}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 1}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn lineEndArrowhead}{\sv 1}}
{\sp{\sn fArrowheadsOK}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1067{\sp{\sn relLeft}{\sv 5805}}{\sp{\sn relTop}{\sv 11800}}
{\sp{\sn relRight}{\sv 5806}}{\sp{\sn relBottom}{\sv 11960}}{\sp{\sn fRelFlipH}{\sv 0}}{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 20}}{\sp{\sn shapePath}{\sv 4}}{\sp{\sn fFillOK}{\sv 0}}{\sp{\sn fFilled}{\sv 0}}{\sp{\sn fArrowheadsOK}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}}}{\shp{\*\shpinst\shplid1068{\sp{\sn relLeft}{\sv 2362}}{\sp{\sn relTop}{\sv 11825}}{\sp{\sn relRight}{\sv 4397}}{\sp{\sn relBottom}{\sv 12374}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 1507328}}{\sp{\sn hspNext}{\sv 1068}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 
\b\insrsid3884484\charrsid8747169 Natur\'e1lne jednotky}{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid3884484\charrsid8747169 
\par }}}}{\shp{\*\shpinst\shplid1069{\sp{\sn relLeft}{\sv 7371}}{\sp{\sn relTop}{\sv 11825}}{\sp{\sn relRight}{\sv 9249}}{\sp{\sn relBottom}{\sv 12540}}{\sp{\sn fRelFlipH}{\sv 0}}
{\sp{\sn fRelFlipV}{\sv 0}}{\sp{\sn shapeType}{\sv 202}}{\sp{\sn lTxid}{\sv 1572864}}{\sp{\sn hspNext}{\sv 1069}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\shptxt \ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid3884484\charrsid8747169 Doba pre\'9e\'edvania/ }{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid3885319\charrsid8747169 pred\'e5\'9eenia \'9eivota}{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid3884484\charrsid8747169 
\par }}}}}{\shprslt{\*\do\dobxcolumn\dobypara\dodhgt8192\dpgroup\dpcount24\dpx0\dpy0\dpxsize8280\dpysize5940\dppolygon\dppolycount4\dpptx0\dppty0\dpptx0\dppty5940\dpptx8280\dppty5940\dpptx8280\dppty0\dpx0\dpy0\dpxsize8280\dpysize5940
\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat0\dplinehollow\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 Typ hodnotenia
\par }}\dpx2880\dpy540\dpxsize2160\dpysize540\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx1620\dppty0\dpptx0\dppty900\dpastartsol\dpastartw2\dpastartl2
\dpx1260\dpy900\dpxsize1620\dpysize900\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx0\dppty0\dpptx1620\dppty900\dpastartsol\dpastartw2\dpastartl2\dpx5040\dpy900\dpxsize1620\dpysize900\dplinew15\dplinecor0\dplinecog0\dplinecob0
\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid8747169\charrsid8747169 Cost-effectivness
\par }}\dpx181\dpy1980\dpxsize2159\dpysize540\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx0\dppty0\dpptx2\dppty360\dpastartsol\dpastartw2\dpastartl2
\dpx1080\dpy2700\dpxsize2\dpysize360\dplinew15\dplinecor0\dplinecog0\dplinecob0\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 
\af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid8747169\charrsid8747169 Zdravotn\'fd stav
\par }}\dpx181\dpy3240\dpxsize2158\dpysize540\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx0\dppty0\dpptx0\dppty360\dpastartsol\dpastartw2\dpastartl2
\dpx1080\dpy3960\dpxsize0\dpysize360\dplinew15\dplinecor0\dplinecog0\dplinecob0\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 
\af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid8747169\charrsid8747169 Meranie v\'fdstupov
\par }}\dpx2880\dpy2784\dpxsize2160\dpysize636\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx0\dppty0\dpptx1\dppty360\dpastartsol\dpastartw2\dpastartl2
\dpx6660\dpy2700\dpxsize1\dpysize360\dplinew15\dplinecor0\dplinecog0\dplinecob0\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 
\af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid8747169\charrsid8747169 Cost-utility
\par }}\dpx5760\dpy1980\dpxsize1980\dpysize540\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 QALY
\par }}\dpx5760\dpy3240\dpxsize2160\dpysize540\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 EQ-5D
\par }}\dpx3240\dpy3960\dpxsize1441\dpysize540\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid8747169\charrsid8747169 HUI
\par 15-D
\par }}\dpx3420\dpy4764\dpxsize1080\dpysize900\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx0\dppty0\dpptx2\dppty540\dpastartsol\dpastartw2\dpastartl2
\dpx3959\dpy3420\dpxsize2\dpysize540\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx0\dppty0\dpptx1\dppty360\dpastartsol\dpastartw2\dpastartl2\dpx6660\dpy3960\dpxsize1\dpysize360\dplinew15\dplinecor0\dplinecog0\dplinecob0
\dpline\dpptx900\dppty0\dpptx0\dppty540\dpastartsol\dpastartw2\dpastartl2\dpx2340\dpy4140\dpxsize900\dpysize540\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx0\dppty0\dpptx1080\dppty540\dpaendsol\dpaendw2\dpaendl2
\dpx2340\dpy4860\dpxsize1080\dpysize540\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx0\dppty0\dpptx1079\dppty540\dpastartsol\dpastartw2\dpastartl2\dpx4681\dpy4140\dpxsize1079\dpysize540\dplinew15\dplinecor0\dplinecog0\dplinecob0
\dpline\dpptx1260\dppty0\dpptx0\dppty540\dpaendsol\dpaendw2\dpaendl2\dpx4500\dpy4860\dpxsize1260\dpysize540\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpline\dpptx0\dppty0\dpptx2\dppty180\dpx3959\dpy4500\dpxsize2\dpysize180
\dplinew15\dplinecor0\dplinecog0\dplinecob0\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 
\fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid3884484\charrsid8747169 Natur\'e1lne jednotky}{\rtlch\fcs1 \ab\af0\afs32 \ltrch\fcs0 \b\fs32\insrsid3884484\charrsid8747169 
\par }}\dpx0\dpy4528\dpxsize2340\dpysize618\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dptxbx\dptxlrtb{\dptxbxtext\ltrpar \pard\plain \ltrpar
\qc \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8747169 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid3884484\charrsid8747169 Doba pre\'9e\'edvania/ }{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid3885319\charrsid8747169 pred\'e5\'9eenia \'9eivota}{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid3884484\charrsid8747169 
\par }}\dpx5760\dpy4528\dpxsize2160\dpysize805\dpfillfgcr255\dpfillfgcg255\dpfillfgcb255\dpfillbgcr255\dpfillbgcg255\dpfillbgcb255\dpfillpat1\dplinew15\dplinecor0\dplinecog0\dplinecob0\dpendgroup\dpx0\dpy0\dpxsize0\dpysize0}}}}{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 
\b\ul\insrsid2432178\charrsid11145242 {\pict{\*\picprop\defshp\shplid1028{\sp{\sn shapeType}{\sv 75}}{\sp{\sn fFlipH}{\sv 0}}{\sp{\sn fFlipV}{\sv 0}}{\sp{\sn fLockRotation}{\sv 1}}{\sp{\sn fLockPosition}{\sv 1}}
{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fPseudoInline}{\sv 1}}{\sp{\sn fLayoutInCell}{\sv 1}}{\sp{\sn fLockPosition}{\sv 1}}{\sp{\sn fLockRotation}{\sv 1}}}\picscalex115\picscaley137\piccropl0\piccropr0\piccropt-4319\piccropb4319
\picw12700\pich7620\picwgoal7200\pichgoal4320\wmetafile8\bliptag417253761\blipupi71{\*\blipuid 18dec98178c71d7bfeec90565d1b92b8}
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000000000000220900004f0d0000c6000000200100000000000000000000000000003f050300cb660400160000000c000000180000000a000000100000000000
0000000000000900000010000000bd060000d6040000250000000c0000000e000080250000000c0000000e000080120000000c00000001000000520000007001
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0000000000000000000000000000000000000000000000000000000000000000000000003500e09a350010000000449e3500c49b3500fa4e3365449e35003c9b
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0180ffff01807fff0180ffffffff00090000000800000008000085ba346701000000000000002c01000025000000372e9001ee00020f0502020204030204ff02
00e1ffac004009000000000000009f01000000000000430061006c0069006200720000000000c09b3500049c3500d62d3d67302e1f68649f3500709b35009832
36671f00000001000000ac9b3500ac9b3500907b34671f000000d49b35001c0583026476000800000000250000000c00000001000000250000000c0000000100
0000250000000c00000001000000180000000c00000000000002540000005400000000000000000000001a00000037000000010000001c8007413f4007410000
00002c000000010000004c000000040000000000000000000000bd060000d60400005000000020001a001b00000046000000280000001c000000474449430200
0000ffffffffffffffffbe060000d7040000000000004600000014000000080000004744494303000000250000000c0000000e000080250000000c0000000e00
00800e000000140000000000000010000000140000000400000003010800050000000b0200000000050000000c0229019e01040000002e0118001c000000fb02
0400020000000000bc02000000ee0102022253797374656d00113f3f3f0000003f3f3f3f083f3f3f000000003f3f3f3f3f00040000002d010000040000002d01
000004000000020101001c000000fb02f5ff0000000000009001000000ee0440002243616c696272690000000000000000000000000000000000000000000000
0000040000002d010100040000002d010100040000002d010100050000000902000000020d000000320a0b00000001000400000000009e01290120000600040000002d010000040000002d010000030000000000}}}}\sectd \ltrsect
\linex0\headery708\footery708\colsx708\endnhere\sectlinegrid360\sectdefaultcl\sectrsid215306\sftnbj \sectd \ltrsect\linex0\headery708\footery708\colsx708\endnhere\sectlinegrid360\sectdefaultcl\sectrsid215306\sftnbj {\*\pnseclvl1
\pnucrm\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl2\pnucltr\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl3\pndec\pnstart1\pnindent720\pnhang {\pntxta .}}{\*\pnseclvl4\pnlcltr\pnstart1\pnindent720\pnhang {\pntxta )}}{\*\pnseclvl5
\pndec\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl6\pnlcltr\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl7\pnlcrm\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\*\pnseclvl8\pnlcltr\pnstart1\pnindent720\pnhang 
{\pntxtb (}{\pntxta )}}{\*\pnseclvl9\pnlcrm\pnstart1\pnindent720\pnhang {\pntxtb (}{\pntxta )}}{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid3884484\charrsid11145242 
\par }\pard\plain \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 
\b\ul\insrsid3884484\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid6446112\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid6702942\charrsid11145242 
\par }\pard \ltrpar\s17\ql \fi-540\li540\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin540\itap0\pararsid6702942 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid6702942\charrsid11145242 IV. \tab }{\rtlch\fcs1 \ab\af0\afs28 
\ltrch\fcs0 \b\caps\fs28\insrsid6702942\charrsid11145242 Popis zdravotnej starostlivosti, popul\'e1cie pacientov a\~potrieb zdravotn\'edckych slu\'9eieb}{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid8747169\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid8747169\charrsid11145242 
\par 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \b\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \hich\af0\dbch\af0\loch\f0 4.1.\tab}}\pard \ltrpar
\s17\qj \fi-540\li540\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls28\ilvl1\adjustright\rin0\lin540\itap0\pararsid6702942 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 Pop}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid3349184\charrsid11145242 i}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 s }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3349184\charrsid11145242  obsahuje}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  nasleduj\'fa
ce prvky:
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid6702942 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f10\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \loch\af10\dbch\af0\hich\f10 \'76\tab}}\pard \ltrpar
\s17\qj \fi-360\li540\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls26\adjustright\rin0\lin540\itap0\pararsid6702942 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 (nenaplnen\'e9) potreby zdravotnej starostlivosti, 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f10\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \loch\af10\dbch\af0\hich\f10 \'76\tab}demograf}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3349184\charrsid11145242 iu}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16256495\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  ak je to d\'f4le\'9eit\'e9 aj soci\'e1lne char}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16256495\charrsid11145242 
akteristiky popul\'e1cie pacientov;}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  aktu\'e1lne dostupn\'e9 mo\'9enosti lie\'e8by,
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f10\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \loch\af10\dbch\af0\hich\f10 \'76\tab}indik\'e1cie, kde sa m\'e1 pou\'9ei\'9d nov\'fd liek}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid15077677\charrsid11145242  alebo in\'e1 technol\'f3gia}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 .
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid6702942 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 
\par Pre jednoduchos\'9d pou\'9e\'edvania v\'fdsledkov rozboru sa odpor\'fa\'e8a jasne \'9apecifikova\'9d: 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}}\pard \ltrpar\s17\qj \fi-360\li540\ri0\widctlpar
\jclisttab\tx180\wrapdefault\aspalpha\aspnum\faauto\ls2\adjustright\rin0\lin540\itap0\pararsid6702942 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 indik\'e1cie lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15077677\charrsid11145242 
 alebo inej technol\'f3gie}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  a\~skupiny (podskupiny) pacientov, na ktor\'e9 sa vz\'9dahuj\'fa v\'fdsledky}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12388114 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid6702942\charrsid11145242  popis aktu\'e1lnych mo\'9enost\'ed lie\'e8by a\~\'farove\'f2 zabezpe\'e8enia zdravotnej starostlivosti (ako s\'fa prim\'e1rna starostlivos\'9d, nemocni\'e8n\'e1 starostlivos\'9d, dom\'e1ca starostlivos\'9d),
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}epidemiologick\'fd profil skupiny pacientov za predpokladu, \'9ee tak\'e9to \'fadaje s
\'fa k\~dispoz\'edcii; typick\'e9 \'fadaje zah\'e0\'f2aj\'fa incidenciu, prevalenciu a\~trendy v\~epidemiologick\'fdch \'fadajoch; v\~pr\'edpade, \'9ee tak\'e9to \'fadaje nie s\'fa k\~dispoz\'edcii, pou\'9eije sa extrapol\'e1cia aj so zd\'f4vodnen\'edm,

\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}k\'be\'fa\'e8ov\'e9 parametre povahy ochorenia (ako s\'fa priemern\'e9
 trvanie choroby, progn\'f3za pre podskupiny pacientov, pridru\'9een\'e9 ochorenia, \'e8asy pre\'9e\'edvania, po\'e8et relapsov a\~spolupr\'e1ca pacientov), ktor\'e9 s\'fa d\'f4le\'9eit\'e9 pre porozumenie efekt\'edvnosti n\'e1kladov na jednotliv\'e9
 formy lie\'e8by.
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid6702942 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid6702942\charrsid11145242 4.2.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  \tab Jasne sa pop\'ed\'9ae liek alebo in\'e1 technol\'f3gia, ktor\'e9 s\'fa predmetom farmako-ekonomick\'e9
ho rozboru. Hlavn\'fdm porovn\'e1vac\'edm prvkom je v\~s\'fa\'e8asnost}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16256495\charrsid11145242 i akceptovan\'e1 \'9atandardn\'e1 lie\'e8ba/-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 y, ktor\'fa
 mieni nov\'fd liek alebo nov\'e1 technol\'f3gia nahradi\'9d. In\'e9 referen\'e8n\'e9 postupy, pri ktor\'fdch sa nepou\'9e\'edvaj\'fa lieky alebo }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8146289\charrsid11145242 in\'e9 technol\'f3gie}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid6702942\charrsid11145242  sa m\'f4\'9eu tie\'9e pou\'9ei\'9d, av\'9aak musia }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8591035\charrsid11145242 sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  od\'f4vodn}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid8591035\charrsid11145242 i\'9d}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 . V\'fdber liekov, zdravotn\'edckych pom\'f4cok}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12717169\charrsid11145242 , dietetick\'fdch potrav
\'edn}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  alebo in\'fdch technol\'f3gi\'ed }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8728593\charrsid11145242 sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 mus\'ed  v\~
kontexte anal\'fdzy jasne uv}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8728593\charrsid11145242 ies\'9d a}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 \~zd\'f4vodn}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8728593\charrsid11145242 i\'9d}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 . Referen\'e8n\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16256495\charrsid11145242 lie\'e8ba/-y}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  je rutinne pou\'9e\'edvan\'e1 
\'9atandardn\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16256495\charrsid11145242 lie\'e8ba/-y}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  v\~be\'9enej praxi (zlat\'fd \'9atandard), ktor\'e1 by mala by\'9d nahraden\'e1 novou potenci
\'e1lne n\'e1kladovo efekt\'edvnou alternat\'edvou. Ak existuje nieko\'beko \'e8asto pou\'9e\'edvan\'fdch alternat\'edvnych sp\'f4sobov lie\'e8by s\~rovnakou \'fa\'e8innos\'9dou, ako referen\'e8n\'e1 lie\'e8ba sa pou\'9eije najlacnej\'9aia alternat\'ed
va. Ak existuje lie\'e8ba, o\~ktorej sa vie, \'9ee je n\'e1kladovo efekt\'edvna (napr. v\~in\'fdch krajin\'e1ch), ale nie je v\~dom\'e1cich podmienkach be\'9ene pou\'9e\'edvan\'e1, prid\'e1 sa do porovn\'e1vacej lie\'e8by. Ak sa na porovnanie vyberie ak
\'fdko\'bevek in\'fd terapeutick\'fd postup, tak\'fdto v\'fdber sa zd\'f4vodn\'ed. V\'fdsledky farmako-ekonomick\'e9ho rozboru platia iba pre indik\'e1cie a\~skupiny pacientov definovan\'e9 na za\'e8iatku anal\'fdzy.
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid8747169\charrsid11145242 
\par 
\par }\pard \ltrpar\s17\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid6702942 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid6702942\charrsid11145242 V. \tab N\'c1KLADY}{\rtlch\fcs1 
\ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid8747169\charrsid11145242 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid8747169\charrsid11145242 
\par 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid6702942 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 \tab Farmako-ekonomick\'fd rozbor rutinne pou\'9e\'edvaj\'fa verejn\'e9
 in\'9atit\'facie na hodnotenie pr\'ednosov pre spolo\'e8nos\'9d}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16256495\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  a\~preto sa m\'f4\'9ee uskuto\'e8\'f2ova\'9d na z\'e1
klade spolo\'e8ensk\'e9ho poh\'beadu, \'e8o znamen\'e1 \'9ee do rozboru }{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\ul\insrsid6702942\charrsid11145242 sa m\'f4\'9eu}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  bra\'9d v\'9aetky n\'e1klady a\~v
\'9aetky zdravotn\'e9 pr\'ednosy vypl\'fdvaj\'face z\~lie\'e8by, bez oh\'beadu na to, kto uhr\'e1dza tieto n\'e1klady a\~kto m\'e1 prospech z\~danej lie\'e8by. 
\par 
\par V\~takom pr\'edpade je potrebn\'e9 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\ul\insrsid6702942\charrsid11145242 oddelene preuk\'e1za\'9d}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242  v\'fdsledky jednotliv\'fdch zlo\'9eiek n\'e1kladov:
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}}\pard \ltrpar
\s17\qj \fi-360\li540\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls15\adjustright\rin0\lin540\itap0\pararsid6702942 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 priame medic\'ednske n\'e1klady
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}priame nemedic\'ednske n\'e1klady
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid6702942\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}n\'e1klady s\'favisiace so zmenou produktivity (nepriame). 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid6702942 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid6702942\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6702942\charrsid11145242 Odpor\'fa\'e8a sa tie\'9e oddeli\'9d n\'e1klady hraden\'e9 z\~verejn\'fdch a\~zo s\'fakromn\'fdch zdrojov.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid6702942\charrsid11145242  
\par V\'9aeobecn\'fdm princ\'edpom je, aby bola anal\'fdza prisp\'f4soben\'e1 poh\'beadu cie\'beov\'fdch skup\'edn, ktor\'e9 chc\'fa oslovi\'9d autori rozboru. Pre krytie v\'fdda}{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid10772443\charrsid11145242 vk}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid6702942\charrsid11145242 ov z\~verejn\'fdch zdrojov je to poh\'bead zdravotn\'fdch pois\'9dovn\'ed. 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\ul\insrsid8747169\charrsid11145242 
\par 
\par 
\par }\pard \ltrpar\s17\qj \fi-720\li720\ri0\pagebb\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid2957075 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid2957075\charrsid11145242 VI. \tab MERANIE ZLEP\'8aENIA ZDRAVIA 

\par }\pard \ltrpar\s17\qj \li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid2957075 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid2957075\charrsid11145242 
\par 
\par }\pard \ltrpar\s17\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 Zdravotn\'fd probl\'e9m, ktor\'fd je predmetom farmako-ekonomick
\'e9ho rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4333452\charrsid11145242  je potrebn\'e9}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242  starostlivo zadefinova\'9d. Probl\'e9m }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid4333452\charrsid11145242 sa pop\'ed\'9ae }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 tak, aby pouk\'e1zal na ot\'e1zky, na ktor\'e9 chceme odpoveda\'9d. Na to, aby anal\'fdza bola d\'f4veryhodn\'e1 a\~transparentn\'e1, }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15736142\charrsid11145242 sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 musia jednozna\'e8ne uvies\'9d jej predpoklady, parametre a\~obmedzenia.
\par }\pard \ltrpar\s17\qj \li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid2957075\charrsid11145242 6.1.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab Meranie \'fa\'e8innosti liekov }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8146289\charrsid11145242 alebo in\'fdch technol\'f3gi\'ed }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 (effectiveness - t.j. zlep\'9aenie zdravia dosiahnut\'e9 v
\~re\'e1lnych podmienkach) sa odpor\'fa\'e8a viac ako meranie p\'f4sobivosti/\'fa\'e8inku (efficacy - t.j. zlep\'9aenie zdravia dosiahnut\'e9 v\~pr\'edsne kontrolovan\'fdch klinick\'fdch podmienkach). T\'ed, ktor\'ed prij\'edmaj\'fa rozhodnutia, sa zauj
\'edmaj\'fa najm\'e4 o\~to, ako bude pr\'edslu\'9an\'fd terapeutick\'fd postup \'fa\'e8inn\'fd v\~ka\'9edodenn\'fdch re\'e1lnych podmienkach. V\~mnoh\'fdch pr\'edpadoch, najm\'e4 v\~pr\'edpade nov\'fdch liekov}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid8146289\charrsid11145242  alebo in\'fdch }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15027311\charrsid11145242 nov\'fdch }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8146289\charrsid11145242 technol\'f3gi\'ed}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid2957075\charrsid11145242 , s\'fa v\'9aak k\~dispoz\'edcii iba v\'fdsledky p\'f4sobivosti/\'fa\'e8inku, ktor\'e9 maj\'fa tendenciu nadhodnocova\'9d \'fa\'e8innos\'9d. V\~tak\'fdchto pr\'ed}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid2652160\charrsid11145242 padoch sa pou\'9eije modelovanie }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 alebo anal\'fdza senzitivity, aby sa extrapolovali \'fadaje o\~p\'f4sobivosti/\'fa\'e8inku na podmienky re\'e1lneho \'9eivota
}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2652160\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242  a\~aby sa zistilo ako rozdielne predpoklady ovplyvnia kone\'e8n\'fd v\'fdsledok anal\'fdzy efekt\'edvnosti n\'e1kladov. 

\par }\pard \ltrpar\s17\qj \li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid2957075\charrsid11145242 6.2.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab V\'fdber miery \'fa\'e8innosti zodpoved\'e1 zvolen\'fdm podmienkam a\~zah\'e0\'f2a kone\'e8n\'e9 (dlhodob\'e9) v\'fdsledky (morbidita, mortalita) a\~zmeny v\~kvalite \'9eivota. Je potrebn\'e9 sa vyhn\'fa\'9d publikovaniu iba \'84n\'e1hradn\'fdch\'93
 v\'fdsledn\'fdch ukazovate\'beov. \'dadaje o\~zlep\'9aen\'ed zdravia m\'f4\'9eu poch\'e1dza\'9d z\~r\'f4znych zdrojov a\~v\'fdber pou\'9eit\'fdch zdrojov je potrebn\'e9 zd\'f4vodni\'9d. Relevantn\'e9 klinick\'e9 \'fadaje pou\'9e\'edvan\'e9
 pri farmako-ekonomick\'fdch rozboroch sa maj\'fa vyh\'beada\'9d, zhodnoti\'9d a\~prezentova\'9d pod\'bea princ\'edpov a\~met\'f3d medic\'edny zalo\'9eenej na d\'f4kazoch  a\~systematick\'fdch preh\'beadov literat\'fary. Uved\'fa sa v\'9aetky vyh\'beadan
\'e9 porovn\'e1vacie \'9at\'fadie a\~s\'fa\'e8asne sa zd\'f4}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2436644\charrsid11145242 vodn}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid417612\charrsid11145242 \'ed}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid2436644\charrsid11145242  v\'fdber porovn\'e1vacej \'9at\'fadie/-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 \'ed  pre farmako-ekonomick\'fd rozbor. V\~pr\'edpade, ak niektor\'e9 z\~dostupn\'fdch \'9at\'fadi\'ed nebud\'fa
 do rozboru zaraden\'e9, uvedie sa aj d\'f4vod nezaradenia. Ak je to mo\'9en\'e9, odpor\'fa\'e8a sa, aby inform\'e1cie o\~u\'9eito\'e8nosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\delrsid12782070\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid2957075\charrsid11145242 pre zdravie vych\'e1dzali z (ve\'bek\'fdch randomizovan\'fdch) klinick\'fdch \'9at\'fadi\'ed alebo systematick\'e9ho preh\'beadu randomizovan\'fdch klinick\'fdch \'9at\'fadi\'ed, ktor\'e9 priamo porovn\'e1vaj\'fa nov\'fa
 technol\'f3giu zdravotnej starostlivosti s\~aktu\'e1lne dostupn\'fdmi technol\'f3giami. Ak to nie je mo\'9en\'e9, zdroj klinickej u\'9eito\'e8nosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\delrsid12782070\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid2957075\charrsid11145242 vych\'e1dza z\~klinick\'fdch \'9at\'fadi\'ed zah\'e0\'f2aj\'facich rovnak\'fa referen\'e8n\'fa technol\'f3giu zdravotnej starostlivosti (napr. placebo). S\'fa\'e8asne sa uvedie, \'9ee neexistuj\'fa \'9e
iadne randomizovan\'e9 klinick\'e9 \'9at\'fadie alebo systematick\'fd preh\'bead bu\'ef nov\'e9ho terapeutick\'e9ho postupu alebo hlavn\'e9ho porovn\'e1vacieho terapeutick\'e9ho postupu}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 /-ov}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 . V\~tomto pr\'edpade je potrebn\'e9 urobi\'9d zoznam v\'9aetk\'fdch relevantn\'fdch nerandomizovan\'fdch klinick\'fdch \'9at\'fadi\'ed a\~od\'f4vodni\'9d v\'fdber \'9at\'fadi\'ed zahrnut\'fd
ch vo\~farmako-ekonomickom rozbore. V\'fdsledky zlep\'9aenia zdravia m\'f4\'9eu poch\'e1dza\'9d z\~in\'fdch \'9at\'fadi\'ed ako s\'fa neexperiment\'e1lne \'9at\'fadie alebo z\~odhadu vych\'e1dzaj\'faceho z\~odborn\'e9ho posudku alebo z\~kombin\'e1cie r
\'f4znych zdrojov. Odborn\'fd posudok nie je n\'e1hrada za racion\'e1lne vedeck\'e9 d\'f4kazy, ale m\'f4\'9ee pom\'f4c\'9d pri interpret\'e1cii v\'fdsledkov \'9at\'fadi\'ed a\~vytvori\'9d r\'e1mec pre farmako-ekonomick\'fd rozbor definovan\'edm pr\'edslu
\'9an\'e9ho miesta novej technol\'f3gie v\~lie\'e8be (indik\'e1cia a\~porovn\'e1vacie technol\'f3gie) ako aj predpoveda\'9d sp\'f4sob vyu\'9eitia zdrojov. Treba v\'9aak poznamena\'9d, \'9ee hore uveden\'e9 zdroje inform\'e1ci\'ed maj\'fa in\'e9 miesto v 
\'84hierarchii d\'f4kazov\'93}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2652160\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242  a\~preto z\~nich vych\'e1dzaj\'face rozhodnutia so sebou nes\'fa in\'fa \'farove\'f2 rizika a\~
neur\'e8itosti, \'e8o sa aj uvedie v\~anal\'fdze. Autori farmako-ekonomick\'fdch rozborov m\'f4\'9eu zhroma\'9edi\'9d svoje vlastn\'e9 \'fadaje alebo m\'f4\'9eu zahrn\'fa\'9d v\'fdsledky zo \'9at\'fadi\'ed vykonan\'fdch in\'fdmi autormi. }{\rtlch\fcs1 
\af0 \ltrch\fcs0 \b\insrsid2957075\charrsid11145242 Oba pr\'edstupy s\'fa prijate\'ben\'e9, ale v\'fdber sa od\'f4vodn\'ed a\~uved\'fa sa obmedzenia zvolen\'fdch met\'f3d.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242  Pri kombinovan\'ed
 v\'fdsledkov \'fa\'e8innosti z\~viac ako jednej existuj\'facej \'9at\'fadie sa dodr\'9eiavaj\'fa met\'f3dy a\~odpor\'fa\'e8ania medic\'edny zalo\'9eenej na d\'f4kazoch a\~systematick\'fdch preh\'beadov literat\'fary. Met\'f3dy pou\'9eit\'e9 pri synt\'e9
ze \'fadajov sa jasne pop\'ed\'9au. Vo\~farmako-ekonomick\'fdch rozboroch sa m\'f4\'9eu pou\'9ei\'9d \'84n\'e1hradn\'e9\'93 v\'fdsledn\'e9 ukazovatele, ak je v\'fdznamn\'e1 asoci\'e1cia medzi predbe\'9en\'fdm a\~kone\'e8n\'fdm v\'fdsledn\'fdm ukazovate
\'beom (morbidita, m}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2652160\charrsid11145242 ortalita, kvalita \'9eivota) }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 alebo \'84n\'e1hradn\'fd\'93 v\'fdsledn\'fd ukazovate\'be
 je klinicky signifikantn\'fd a\~toto zlep\'9aenie je dlho trvaj\'face. 
\par }\pard \ltrpar\s17\qj \li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \b\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \hich\af0\dbch\af0\loch\f0 6.3.\tab}}\pard \ltrpar\s17\qj \fi-720\li720\ri0\widctlpar
\jclisttab\tx720\wrapdefault\aspalpha\aspnum\faauto\ls29\ilvl1\adjustright\rin0\lin720\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 V\'fdsledky posudzovan\'fdch klinick\'fdch \'9at\'fadi\'ed  sa  prezent}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11018028\charrsid11145242 uj\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242  individu\'e1lne v\~tabu\'bekovej forme:
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}}\pard \ltrpar
\s17\qj \fi-360\li540\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls16\adjustright\rin0\lin540\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 ako zdroje d\'e1t vr\'e1tane roku \'9at\'fadie,
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}odkazu na literat\'faru,
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}usporiadania \'9at\'fadie, krajiny v\~ktor\'fdch sa \'9at\'fadia vykon\'e1vala, 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}popisu \'9atudovanej popul\'e1cie vr\'e1tane po\'e8tu pacientov, 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}meran\'fdch klinick\'fdch v\'fdsledn\'fdch ukazovate\'beov, 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}popisu prirodzenej jednotky merania, 
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}ve\'bekosti zmeny (redukcia relat\'edvneho, absol\'fatneho rizika, NNT \endash  po\'e8
et pacientov, ktor\'fdch je treba lie\'e8i\'9d a\~NNH \endash  po\'e8et pacientov, ktor\'fdch je potrebn\'e9 vystavi\'9d rizikov\'e9mu faktoru, aby do\'9alo k\~po\'9akodeniu zdravia)
\par {\listtext\pard\plain\ltrpar \s17 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}\'9atatistickej v\'fdznamnosti (uvies\'9d bodov\'e9 odhady a\~95% intervaly spo\'be
ahlivosti). 
\par }\pard \ltrpar\s17\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid2957075\charrsid11145242 
\par Ak je viac ako jedna klinick\'e1 premenn\'e1, tieto premenn\'e9 sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid7149073\charrsid11145242 uv\'e1dzaj\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid2957075\charrsid11145242  v\~samostatn\'fdch tabu\'bek\'e1
ch. Pre zov\'9aeobecnenie v\'fdsledkov je d\'f4le\'9eit\'e9, aby sa \'fadaje uviedli jasne. Ak sa v\~klinick\'fdch \'9at\'fadi\'e1ch meralo viacero v\'fdsledn\'fdch ukazovate\'beov, v\'9aetky v\'fdsledn\'e9 ukazovatele  sa  u}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \i\insrsid7149073\charrsid11145242 v}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid11018028\charrsid11145242 \'e1dzaj\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid2957075\charrsid11145242  v\~tabu\'bekovej forme. 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid2957075\charrsid11145242 6.4.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242  \tab Pou\'9eitie modelovania pri farmako-ekonomickom rozbore je prijate\'ben\'e9, ak sa model uvedie transparentn\'fd
m sp\'f4sobom}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2436644\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242  a\~ak sk\'f4r zah\'e0\'f2a ako nahr\'e1dza vedeck\'e9 poznatky. 
\par }\pard\plain \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid2957075\charrsid11145242 Pri farmako-ekonomickom rozbore m\'f4\'9ee by\'9d potrebn\'e9 pou\'9eitie modelovania pri rozhodovan\'ed. Pre pou\'9eitie modelovania je potrebn\'e9 uvies\'9d d\'f4vody. T\'fdmito d\'f4vodmi zvy\'e8ajne s\'fa: 
\par {\listtext\pard\plain\ltrpar \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}}\pard \ltrpar
\qj \fi-360\li540\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls4\adjustright\rin0\lin540\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 Extrapol\'e1cia \'fadajov o\~vplyve na v\'fdsledky \'fa\'e8innosti.
\par {\listtext\pard\plain\ltrpar \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}Extrapol\'e1cia kr\'e1tkodob\'fdch alebo \'84n\'e1hradn\'fdch\'93 klinick\'fdch v\'fdsledn
\'fdch ukazovate\'beov na dlhodob\'e9 alebo kone\'e8n\'e9 pr\'ednosy pre zdravie (napr. zn\'ed\'9eenie krvn\'e9ho tlaku na v\'fdsledky mortality a\~morbidity). 
\par {\listtext\pard\plain\ltrpar \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}Integr\'e1cia \'fadajov z\~r\'f4znych zdrojov alebo \'fadajov vz\'9dahuj\'fac
ich sa na rozdielne v\'fdsledne ukazovatele komplexn\'e9ho rozboru.
\par {\listtext\pard\plain\ltrpar \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}Synt\'e9za \'fadajov o\~n\'e1kladoch a\~klinick\'fdch v\'fdsledn\'fdch ukazovate\'beoch vz
\'9dahuj\'facich sa na liek}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8146289\charrsid11145242  alebo in\'e9 technol\'f3gie}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 . 
\par {\listtext\pard\plain\ltrpar \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid2957075\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}Ak nie s\'fa k\~dispoz\'edcii randomizovan\'e9 klinick\'e9 \'9at\'fadie, ktor\'e9
 priamo porovn\'e1vaj\'fa nov\'fa technol\'f3giu s\~aktu\'e1lne dostupn\'fdmi technol\'f3giami. 
\par }\pard \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2436644\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 Anal\'fdza senzitivity sa vykon\'e1va na neur\'e8it\'e9 \'fadaje zahrnut\'e9 v\~model}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3352001\charrsid11145242 i}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid2957075\charrsid11145242 , aby sa overila kone\'e8n\'e1 efekt\'edvnos\'9d n\'e1kladov. Z\~toho d\'f4vodu, \'9ee farmako-ekonomick\'e9 rozbory m\'f4\'9eu by\'9d ve\'bemi zlo\'9eit\'e9, je obzvl\'e1\'9a\'9d d\'f4le\'9eit\'e9 jasn\'e9 udanie vstupn
\'fdch \'fadajov a\~met\'f3d pou\'9eit\'fdch pri modelovan\'ed, \'e8o }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2436644\charrsid11145242 na}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 pom\'f4\'9ee porozumeniu a\~prijate\'benosti v\'fd
sledkov rozboru.
\par }\pard \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
\par }\pard \ltrpar\qj \li360\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin360\itap0\pararsid1864751 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid543024\charrsid11145242 
\par }\pard \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid2957075\charrsid11145242 
\par 
\par }\pard \ltrpar\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid2957075 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4736060\charrsid11145242 VII. }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 
\b\fs28\insrsid2957075\charrsid11145242 \tab }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4736060\charrsid11145242 MERANIE N\'c1KLADOV}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \ab\af0\afs28 
\ltrch\fcs0 \b\fs28\insrsid15430209\charrsid11145242 
\par }\pard \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15430209 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid15430209\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 7.1.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 \tab }
{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Poh\'be}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15430209\charrsid11145242 ad na stanovenie n\'e1kladov m\'e1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  by\'9d rovnak\'fd
 ako je poh\'bead }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . Rozsah n\'e1kladov zahrnut\'fdch v}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10974372\charrsid11145242 
 anal\'fdze }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 \~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10974372\charrsid11145242 farmako-ekonomick\'e9ho rozboru }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 z\'e1vis\'ed
 na poh\'beade }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid15430209\charrsid11145242 
\par }\pard \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15430209 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 Napr\'edklad}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid2436644\charrsid11145242  -}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid8257923\charrsid11145242 rozbor pripraven\'fd}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242  
\'fazko zameran\'fdm n\'e1kupcom zdravotnej starostlivosti alebo poskytovate\'beom nemocni\'e8nej starostli}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid8257923\charrsid11145242 vosti by nezobral}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid16411968\charrsid11145242  do \'favahy \'e8as \'beud\'ed poskytuj\'facich opateru, zatia\'be \'e8o }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid8257923\charrsid11145242 rozbor pripraven\'fd}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid16411968\charrsid11145242  zo \'9air\'9aieho spol}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid8257923\charrsid11145242 o\'e8ensk\'e9ho poh\'beadu by to zahrnul}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 .}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 
\par }\pard \ltrpar\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4736060\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }\pard\plain \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 \rtlch\fcs1 \af0\afs24\alang1025 \ltrch\fcs0 \fs24\lang1051\langfe1033\cgrid\langnp1051\langfenp1033 {\rtlch\fcs1 \af0 
\ltrch\fcs0 \b\insrsid4736060\charrsid11145242 7.2.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 \tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 V\'fdber}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid15430209\charrsid11145242  cien pou\'9eit\'fdch v\~anal\'fdze m\'e1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  by\'9d v\~zhode s\~poh\'beadom (perspekt\'edvou) }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 
rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10974372\charrsid11145242  a\~vych\'e1dza z\~\'faradne ur\'e8en\'fdch cien v\~\'e8ase predkladania farmako-ekonomick\'e9ho rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15430209\charrsid11145242 . Ceny pou\'9e
it\'e9 v\~anal\'fdze maj\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  by\'9d cenami relevantn\'fdmi pre definovan\'fa cie\'beov\'fa skupinu }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 rozboru}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242 . }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15430209\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 7.3.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4396314\charrsid11145242 Farmako-e}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11162956\charrsid11145242 konomick\'fd rozbor}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid15430209\charrsid11145242 v\~zdravotn\'edctve uv\'e1dza}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  \'fadaje o\~pou\'9eit\'ed finan\'e8n\'fdch zdrojov a\~c}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid3613402\charrsid11145242 eny samostatne. Je potrebn\'e9 jasne}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  uvies\'9d zdroje \'fadajov o\~financi\'e1ch. Finan\'e8n\'e9 zdroje pou\'9eit\'e9 po\'e8as lie\'e8by (po\'e8et n\'e1v\'9a
tev lek\'e1ra a\~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 po\'e8et vy\'9aetren\'ed) a\~ceny zdrojov sa uv\'e1dzaj\'fa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 samostatne v\~tabu\'bekovej forme. To napom\'e1
ha reprodukovate\'benosti a\~jasn\'e9mu porozumeniu anal\'fdzy. Toto je obzvl\'e1\'9a\'9d d\'f4le\'9eit\'e9, ak sa pri hodnoten\'ed vyu\'9e\'edva modelovanie.
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid543024\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 7.4.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 V\~pr\'edpade }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 rozborov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 , ktor\'e9 prevezm\'fa \'fadaje o
\~vyu\'9e\'edvan\'ed zdrojov zo zahrani\'e8n\'fdch klinick\'fdch \'9at\'fadi\'ed alebo }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11162956\charrsid11145242 farmako-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 ekonomick\'fdch}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid11162956\charrsid11145242  rozborov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 v\~zdravotn\'edctve, }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242 sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 porovn\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 klinick\'e1 prax v\~zahrani\'e8n\'fdch podmienkach so slovensk\'fd
mi podmienkami. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 Pr\'edpadov\'e1 (b}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 ase-case}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 )}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242  anal\'fdza (v\'fdsledky anal\'fdzy efekt\'edvnosti n\'e1kladov, ktor\'e9 s\'fa ur\'e8en\'e9 pri hlavn\'fd}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 ch predpokladoch modelu) uv\'e1dza}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  priamu \'fapravu \'fadajov o\~vyu\'9e\'edvan\'ed zdrojov zo zahrani\'e8nej \'9at\'fadie. Ak porovnanie preuk\'e1\'9ee, \'9ee medzi dvomi krajinami sa klinick\'e1}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid3613402\charrsid11145242  prax l\'ed\'9ai, pr\'edpadov\'e1 (base-case) anal\'fdza sa dop\'e5\'f2a}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  anal\'fdzou, ktor\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid3613402\charrsid11145242 uprav\'ed}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  rozdiely v\~klinickej praxi. Zahrani\'e8n\'e9 a\~slovensk\'e9 klinick\'e9 postupy v\~lie\'e8be sa m\'f4\'9eu l\'ed\'9ai\'9d  a tieto rozdiely m\'f4
\'9eu zah\'e0\'f2a\'9d r\'f4zne vzory vyu\'9e\'edvania zdrojov po\'e8as lie\'e8by. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid3613402 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid3613402\charrsid11145242 Napr\'edklad: t}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid16411968\charrsid11145242 ypick\'e9 vzory vyu\'9e\'edvania zdrojov (ako s\'fa po\'e8et n\'e1v\'9atev, priemern\'e1 d\'e5\'9eka hospitaliz\'e1cie)  m\'f4\'9eu by\'9d na Slovensku vy\'9a\'9aie alebo ni\'9e\'9aie ako v\~zahrani\'e8\'ed. Ak je situ
\'e1cia na Slovensku odli\'9an\'e1, prisp\'f4sobenie by sa malo prebra\'9d v\~dopl\'f2uj\'facej anal\'fdze. Ak sa zdroje meraj\'fa v\~klinickej \'9at\'fadii, je d\'f4le\'9eit\'e9 rozli\'9aova\'9d medzi zdrojmi vyu\'9e\'edvan\'fdmi v\~be\'9enej praxi a\~t
\'fdmi, ktor\'e9 sa vyu\'9e\'edvaj\'fa v\~podmienkach klinickej \'9at\'fadie. 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 7.5.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Ak n\'e1klady spadaj\'fa pod r\'f4zne rozpo\'e8ty, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9262081\charrsid11145242 uved\'fa sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  podrobnosti o\~vplyve }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid13590509\charrsid11145242 lieku }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15473606\charrsid11145242 alebo inej technol\'f3gie }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242 na r\'f4zne rozpo\'e8ty na zdravotn\'fa starostlivos\'9d. Toto je d\'f4le\'9eit\'e9 pri porovn\'e1van\'ed r\'f4znych foriem lie\'e8by, ktor\'e9 ved\'fa k\~n\'e1kladom alebo \'faspor\'e1m v\~r\'f4znych rozpo\'e8toch. }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9842691\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 Napr\'edklad}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid3613402\charrsid11145242 :}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242  test na antibiotik\'e1 m\'f4\'9ee sp\'f4
sobova\'9d dodato\'e8n\'e9 n\'e1klady pre nemocnicu alebo ambulantn\'fa starostlivos\'9d a\~m\'f4\'9ee vies\'9d k\~\'faspor\'e1m v\~rozpo\'e8te na lieky. Preto je d\'f4le\'9eit\'e9, aby anal\'fdza jasne ur\'e8ila, kde doch\'e1dza k\~vzniku n\'e1
kladov alebo k\~ich \'faspor\'e1m. To umo\'9e\'f2uje t\'fdm, ktor\'ed prij\'edmaj\'fa rozhodnutia urobi\'9d tieto rozhodnutia pri lep\'9aej informovanosti a\~\~pl\'e1nova\'9d rozpo\'e8ty na zdravotn\'fa starostlivos\'9d ber\'fac do \'favahy \'fapln\'e9 d
\'f4sledky zaradenia nov\'fdch n\'e1kladovo efekt\'edvnych sp\'f4sobov lie\'e8by.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
\par 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 7.6.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Ak sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 rozbor}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  vykon\'e1va z\~poh\'beadu n\'e1
kupcu zdravotnej starostlivosti, k\~\'fadajom o\~vyu\'9e\'edvan\'ed zdravotn\'fdch zdrojov }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 sa via\'9ee}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  najni\'9e\'9aia mo\'9en
\'e1 cena. Podobne aj finan\'e8n\'e1 spolu\'fa\'e8as\'9d pacientov }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 sa vypo\'e8\'edta}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  ako potrebn\'e1 minim\'e1lna finan\'e8n
\'e1 spolu\'fa\'e8as\'9d, ktor\'fa mus\'ed pacient zaplati\'9d, aby dostal pr\'edslu\'9an\'fd typ lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11676922\charrsid11145242 , inej technol\'f3gie }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
 alebo }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11676922\charrsid11145242 zdravotnej starostlivosti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . N\'e1kupca zdravotnej starostlivosti sa sna\'9e\'ed maximalizova\'9d pr\'ed
nos pre zdravie pri limitovan\'fdch zdrojoch a preto m\'e1 z\'e1ujem nahradi\'9d aktu\'e1lnu n\'e1kladovo najefekt\'edvnej\'9aiu alternat\'edvu novou technol\'f3giou. Z\'e1rove\'f2 sa n\'e1kupcovia zdravotnej starostlivosti sna\'9eia ovplyvni\'9d spr\'e1
vanie poskytovate\'beov, aby tak u\'beah\'e8ili dodr\'9eiavanie n\'e1kladovo efekt\'edvnych postupov. 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 7.7.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Z}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 o spolo\'e8ensk\'e9ho poh\'beadu sa m\'f4\'9eu}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  bra\'9d
 do \'favahy n\'e1klady na produkti}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 vitu. N\'e1klady na produktivitu sa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  v}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid4473479\charrsid11145242 o v\'fdchodiskovej/z\'e1kladnej}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3613402\charrsid11145242 \~(}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 base-case}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid3613402\charrsid11145242 )}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242  anal\'fdze vypo\'e8\'edtaj\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  ako hrub}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid11888800\charrsid11145242 \'e1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  priemern}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11888800\charrsid11145242 \'e1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11888800\charrsid11145242 mzda }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 pacientov v\~akt\'edvnom veku. Takisto sa\~m\'f4\'9ee overi\'9d vplyv pou\'9eitia in\'fdch met\'f3d v\'fdpo\'e8tu. N\'e1
klady na produktivitu spadaj\'fa mimo zdravotn\'fa starostlivos\'9d a\~s\'favisia s\~vplyvom v\'fdkonu zdravotnej starostlivosti na produktivitu jednotlivcov. Pri pou}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 \'9eit\'ed spolo\'e8
enskej perspekt\'edvy sa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  n\'e1klady}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242  na produktivitu pou\'9eij\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  iba vtedy, ak s\'fa signifikantn\'e9. V\~d\'f4sledku neur\'e8itosti metodol\'f3gie v\'fdpo\'e8tu n\'e1kladov na produktivitu by sa mal vplyv pou\'9eitia r\'f4znych pr\'edstupov overi\'9d v\~anal\'fdze }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid12782070\charrsid11145242 senzitivity}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . Ak s\'fa n\'e1klady na produktivitu vysok\'e9, mali by sa uv\'e1dza\'9d samostatne. }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid1473308\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid1473308 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid1473308\charrsid11145242 Napr\'edklad: }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid13334870\charrsid11145242 z }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 \~d\'f4vodu jednoduchosti a\~\'9atandardiz\'e1cie v\'fdsledkov sa v\~pr\'edpade akt\'edvnej popul\'e1cie odpor\'fa\'e8a vypo\'e8\'edta\'9d ak\'fako
\'bevek absenciu v\~pr\'e1ci z\~ofici\'e1lnej hrubej (vr\'e1tane pr\'edspevkov na soci\'e1lne poistenie) dom\'e1cej priemernej mzdy. V\~pr\'edpade, ke\'ef sa n\'e1klady na produktivitu pova\'9euj\'fa za d\'f4le\'9eit\'e9,  pomer n\'e1kladov a\~efekt\'ed
vnosti by sa mal vypo\'e8\'edta\'9d dvakr\'e1t, raz so zahrnut\'edm n\'e1kladov na produktivitu a\~raz bez nich. 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\i\insrsid351651 I}{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\i\insrsid1473308\charrsid11145242 de o\~doplnkov\'fa anal\'fdzu, ktor\'fa predkladate\'be m\'f4\'9ee doplni\'9d ku farmako-ekonomick\'e9mu rozboru, av\'9aak v\'fdsledky s
\'fa uveden\'e9 samostatne.
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid1473308\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 7.8.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Soci\'e1lne }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 n\'e1klady}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  ako s\'fa nemocensk\'e9 d\'e1
vky, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid13205129\charrsid11145242 d\'e1vky}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  v\~nezamestnanosti }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15806135\charrsid11145242 a\~in\'e9 d\'e1vky }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 sa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 neber\'fa do \'favahy}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  ako n\'e1klady nez\'e1visle od perspekt\'edvy (poh\'beadu) }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . Av\'9aak v}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3935653 \~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 pr\'edpadoch}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3935653 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  ke\'ef ich cie
\'beov\'e1 skupina pova\'9euje za v\'fdznamn\'fd faktor (napr. pre \'fa\'e8ely pl\'e1novania alebo z\~h\'beadiska rovnosti), m\'f4\'9ee sa uvies\'9d vplyv pou\'9eitia }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 lieku }{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid15473606\charrsid11145242 alebo in\'fdch technol\'f3gi\'ed }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 na soci\'e1lne n\'e1klady}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . Ak  v\'9aak nov
\'fd }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 liek}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15473606\charrsid11145242  alebo in\'e1 nov\'e1 technol\'f3gia}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242  }{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid15473606\charrsid11145242 podroben\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 farmako-eknomick\'e9mu rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  m\'e1 v\'fdzn}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid1473308\charrsid11145242 amn\'fd vplyv na soci\'e1lne n\'e1klady}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 , \'e8o m\'f4\'9ee by\'9d obzvl\'e1\'9a\'9d zauj\'edmav\'e9 pre cie\'beov\'fa skupinu, je mo\'9en\'e9
 zd\'f4razni\'9d }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3935653\charrsid11145242 to }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 v\~doplnkovej anal\'fdze. 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15099274 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\i\insrsid351651 I}{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\i\insrsid15099274\charrsid11145242 de o\~doplnkov
\'fa anal\'fdzu, ktor\'fa predkladate\'be m\'f4\'9ee doplni\'9d ku farmako-ekonomick\'e9mu rozboru, av\'9aak v\'fdsledky s\'fa uveden\'e9 samostatne.
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid13590509\charrsid11145242 
\par }\pard \ltrpar\s19\ql \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid2957075 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid2957075\charrsid11145242 VIII.\tab VPLYV \'c8ASU V\~AN}{\rtlch\fcs1 
\ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4736060\charrsid11145242 AL\'ddZACH FARMAKO}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid6773538\charrsid11145242 \_}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4736060\charrsid11145242 EKONOMICK
\'c9HO ROZBORU}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\strike\fs28\insrsid15099274\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx720\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15099274 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\strike\insrsid15099274\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\strike\insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 8.1.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 \'c8asov\'fd horizont }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid15099274\charrsid11145242 m\'e1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  by\'9d dostato\'e8ne dlh\'fd na obsiahnutie v\'9aetk\'fdch v\'fdznamn\'fdch klinick\'fdch d\'f4sledkov ako aj d\'f4sledkov na n\'e1
klady, ktor\'e9 priamo s\'favisia s}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11676922\charrsid11145242 \~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid13590509\charrsid11145242 liekom}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11676922\charrsid11145242  }{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid15473606\charrsid11145242 alebo inou technol\'f3giou}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid13590509\charrsid11145242 , }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15473606\charrsid11145242 ktor\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid13590509\charrsid11145242 podlieha rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . Je d\'f4le\'9eit\'e9, aby sa vzali do \'favahy v\'9aetky v\'fdznamn\'e9 d\'f4sledky pre zdravie a\~n\'e1klady priamo s\'favisiace s}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid13590509\charrsid11145242  liekom}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 \~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15473606\charrsid11145242 alebo inou technol\'f3giou}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242 . To znamen\'e1, \'9ee \'e8asov\'e9 obdobie pou\'9eit\'e9 v\~anal\'fdze }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 je jeden lie\'e8ebn\'fd cyklus alebo kalend\'e1rny rok a\~potom \'efal
\'9a\'edch p\'e4\'9d nasleduj\'facich rokov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  na obsiahnutie dlhodob\'fdch vplyvov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid5055327 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 nie}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  len kr\'e1tkodob\'fdch n\'e1sledkov. }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 
\b\strike\insrsid15099274\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15099274 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\strike\insrsid15099274\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\strike\insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 8.2.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Ceny pri }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 v\'fdpo\'e8te}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  n\'e1kladov}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16401842\charrsid11145242  na lieky}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12262975\charrsid11145242  alebo in\'fa technol\'f3giu}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16401842\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16404535\charrsid11145242 vych\'e1dza}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 j\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16404535\charrsid11145242  z\~\'faradne ur\'e8en\'fdch cien v\~\'e8ase predkladania farmako-ekonomick
\'e9ho rozbor}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 u}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 .}{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\strike\insrsid15099274\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15099274 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 8.3.}{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 
\b\insrsid2957075\charrsid11145242 \tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 V\~pr\'edpade }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
 s\~\'e8asov\'fdm ho}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 rizontom dlh\'9a\'edm ako jeden rok sa ber\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  do \'favahy princ\'edpy \'e8asovej preferencie a\~n\'e1
kladov straten\'fdch pr\'edle\'9eitost\'ed na invest\'edcie cez korekciu pod\'bea diskontnej sadzby. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11150428\charrsid11145242 V\~t\'fdchto pr\'edpadoch sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid15099274\charrsid11145242 pou\'9e\'edva}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11150428\charrsid11145242  v\'9aeobecn\'e1 ekonomick\'e1 met\'f3da korekcie pod\'bea diskontnej sadzby. }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 
\b\strike\insrsid15099274\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11150428\charrsid11145242 D\'f4vodom korekcie bud\'facich n\'e1kladov pod\'be
a diskontnej sadzby na ich s\'fa\'e8asn\'fa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 hodnotu s\'fa dva hlavn\'e9 princ\'edpy:
\par {\listtext\pard\plain\ltrpar \s19 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid15099274\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}}\pard \ltrpar
\s19\qj \fi-360\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls7\adjustright\rin0\lin720\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 p}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11150428\charrsid11145242 rinc
\'edpy \'e8asovej preferencie }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\strike\insrsid15099274\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s19 \rtlch\fcs1 \af0 \ltrch\fcs0 \f3\lang1051\langfe1033\langfenp1033\insrsid15099274\charrsid11145242 \loch\af3\dbch\af0\hich\f3 \'b7\tab}}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 princ\'edp }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11876163\charrsid11145242 oportunitn\'fdch investi\'e8n\'fdch }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11150428\charrsid11145242 n\'e1kladov }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\strike\insrsid15099274\charrsid11145242 

\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15099274 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 V\~praxi to znamen\'e1, }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid11150428\charrsid11145242 \'9ee ur\'e8it\'e1 suma pe\'f2az\'ed v\~s\'fa\'e8asnosti m\'e1 v\'e4\'e8\'9aiu hodnotu  ako rovnak\'e1 suma pe\'f2az\'ed v\~bud\'facnosti, preto\'9ee peniaze v\~s\'fa\'e8asnosti s\'fa ist\'e9 a\~m\'f4\'9eu sa investova
\'9d na vytvorenie zisku v\~bud\'facnosti. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 
\par 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid6321418\charrsid11145242 
\par }\pard \ltrpar\s19\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid2957075 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4736060\charrsid11145242 IX. }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 
\b\fs28\insrsid2957075\charrsid11145242 \tab }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4736060\charrsid11145242 KOMBIN\'c1CIA ZDRAVOTN\'ddCH PR\'cdNOSOV A N\'c1KLADOV}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 
\b\fs28\insrsid15099274\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4736060\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx720\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 9.1.}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid2957075\charrsid11145242 \tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 J}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15099274\charrsid11145242 e potrebn\'e9 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 uv\'e1
dza\'9d }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 jasne }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 v\'fdsledky celkov\'fdch n\'e1kladov a celkov\'fdch zdravotn\'fdch pr\'ednosov porovn\'e1van\'fdch}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid13984976\charrsid11145242  liekov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242  alebo in\'fdch tec}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11676922\charrsid11145242 h}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9138444\charrsid11145242 nol\'f3gi\'ed}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 , }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2778869 pre}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242  reprodukovate\'benos\'9d a\~
bud\'face vyu\'9e\'edvanie}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  \'fadajov v\~in\'fdch }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid13984976\charrsid11145242 farmako-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
ekonomick\'fdch anal\'fdzach}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 . S\'fa\'e8asne je potrebn\'e9}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  jasne }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid8028133\charrsid11145242 uv\'e1dza\'9d}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  v\'fdsledky celkov\'fdch n\'e1kladov a\~celkov\'fdch zdravotn\'fdch pr\'ednosov porovn\'e1van\'fdch alternat\'edvnych}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid13984976\charrsid11145242  liekov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242  a in\'fdch technol\'f3gi\'ed}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid13984976\charrsid11145242  alebo in\'fdch lie\'e8ebn\'fdch postupov.}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid8028133\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 Nie je dostato\'e8n\'e9 uv\'e1dza\'9d iba priemern\'e9 alebo pr\'ed
rastkov\'e9 pomery n\'e1kladov a\~efekt\'edvnosti.}{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid8028133\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8028133 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 9.2.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Ak existuje dominantn\'e1 strat\'e9gia, jasne }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 sa tento fakt uvedie}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  a\~nie je potrebn\'e9 uv\'e1dza\'9d pr\'edrastkov\'e9 pomery n\'e1kladov a\~efekt\'edvnosti a/alebo pomery \'fa\'e8elnosti n\'e1kladov. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 Ak v\'9aak anal\'fd
za }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12782070\charrsid11145242 senzitivity }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 preuk\'e1\'9ee, \'9ee liek}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242  alebo in\'e1 technol
\'f3gia}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 , }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242 ktor\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 je predmetom farmako-ekonomick\'e9
ho rozboru str\'e1ca v\~niektor\'fdch pr\'edpadoch svoju dominanciu, je }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4528615\charrsid11145242 potrebn\'e9}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242  uvies\'9d pr\'edrastkov\'fd pomer n\'e1
kladov a\~efekt\'edvnosti pre najhor\'9a\'ed scen\'e1r. }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid8028133\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8028133 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Ak v\'fdsledky preuk\'e1\'9eu, \'9ee efekt\'edvnej\'9aia lie\'e8
ba je takisto aj najlacnej\'9aia, t\'e1to alternat\'edva  sa  pova\'9e}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4130126\charrsid11145242 uje}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  za n\'e1kladovo efekt\'edvnu. V\~pr\'ed
pade rovnakej efekt\'edvnosti by sa v\'fdkon s\~ni\'9e\'9a\'edmi n\'e1kladmi mal pova\'9eova\'9d za n\'e1kladovo efekt\'edvny. 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid8028133\charrsid11145242 Pr\'edrastkov\'fd pomer n\'e1kladov a\~efekt\'edvnosti }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 sa  vypo\'e8\'edta ako rozdiel medzi celkov\'fdmi n\'e1
kladmi alternat\'edvnych sp\'f4sobov lie\'e8by delen\'fd rozdielom medzi celkov\'fdmi pr\'ednosmi pre zdravie z\'edskan\'fdmi alternat\'edvnymi sp\'f4sobmi lie\'e8by. Tento pomer ud\'e1va dodato\'e8n\'e9 n\'e1klady na jednotku zlep\'9aenia zdravia, ktor
\'e9 mo\'9eno dosiahnu\'9d v\'fdberom efekt\'edvnej\'9aieho variantu lie\'e8by. 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242 
\par 
\par 
\par 
\par }\pard \ltrpar\s19\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid2957075 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid15285141 \page }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 
\b\fs28\insrsid4736060\charrsid11145242 X. }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid2957075\charrsid11145242 \tab }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4736060\charrsid11145242 SILA A\~ZOV\'8aEOBECNITE\'bcNOS\'8d V\'dd
SLEDKOV ROZBORU}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid8028133\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4736060\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 10.1.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 \tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12021586\charrsid11145242 Pomocou anal\'fdzy senzitivity }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid8028133\charrsid11145242  sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12021586\charrsid11145242 over\'ed }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 vplyv}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  neur\'e8it\'fdch faktorov na kone\'e8n\'e9 v\'fdsledky efekt\'edvnosti n\'e1kladov a\~tieto v\'fdsledky sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 uv}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid12021586\charrsid11145242 e}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 d\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  kvantitat\'edvnym sp\'f4sobom. }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid15608336\charrsid11145242 Ak s\'fa vstupn\'e9 \'fadaje pou\'9eit\'e9 v\~rozbore neur\'e8it\'e9}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14818114\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid7484406\charrsid11145242 je nevyhnutn\'e9 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 vykona\'9d anal\'fdzu }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12782070\charrsid11145242 senzitivity}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242 , aby sa zistilo ako sa kone\'e8n\'e1 efekt\'edvnos\'9d n\'e1kladov men\'ed pri odli\'9an\'fdch predpokladoch. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7484406\charrsid11145242 Premenn\'e9, ktor\'e9 s\'fa
 zdrojom neistoty, je potrebn\'e9 meni\'9d v\~celom teoreticky mo\'9enom intervale, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 minim\'e1lne \'b1}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7484406\charrsid11145242 30%}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid15608336\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid7484406\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Pomocou inform\'e1ci\'ed z\'edskan\'fdch pri anal\'fdze }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid12782070\charrsid11145242 senzitivity}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 sa m\'f4\'9eu lep\'9aie pos\'fadi\'9d rizik\'e1 t\'fdkaj\'fa
ce sa rozhodnut\'ed na z\'e1klade v\'fdsledkov }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . Ak sa }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 
pou\'9eije}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  modelovanie, }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8028133\charrsid11145242 vykonaj\'fa sa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  jednocestn\'e9 anal
\'fdzy }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12782070\charrsid11145242 senzitivity}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 na v\'9aetky neur\'e8it\'e9 premenn\'e9
 pri pou\'9eit\'ed krajn\'fdch hodn\'f4t. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8671414 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4736060\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 10.2.}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid2957075\charrsid11145242 \tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 Ak sa klinick\'e1 \'fa\'e8innos\'9d alebo efekt\'edvnos\'9d n\'e1kladov v\~ur\'e8it\'fdch podskupin\'e1ch pacientov (ako s\'fa vysoko rizikov\'ed
 pacienti) v\'fdrazne }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid408450\charrsid11145242 odli\'9auje}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14818114\charrsid11145242 , }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid408450\charrsid11145242 je }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242  potrebn\'e1 anal\'fdza podskup\'edn.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 V\~takomto pr\'edpade anal\'fdza podskup\'edn pom\'f4\'9ee n\'e1js
\'9d sp\'f4sob (napr. liek }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid9138444\charrsid11145242 alebo in\'e1 technol\'f3gia }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 prvej vo\'beby, liek }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid9138444\charrsid11145242 alebo in\'e1 technol\'f3gia }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 druhej vo\'beby iba pre skupiny rezistentn\'e9 na lie\'e8bu) ako maximalizova\'9d zdravotn\'e9 pr\'ednosy z\~dostupn\'fd
ch zdrojov. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8671414 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par {\listtext\pard\plain\ltrpar \s19 \rtlch\fcs1 \af0 \ltrch\fcs0 \b\lang1051\langfe1033\langfenp1033\insrsid8671414\charrsid11145242 \hich\af0\dbch\af0\loch\f0 10.3.\tab}}\pard \ltrpar
\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\ls30\ilvl1\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 Vo v\'fdsledkoch rozboru sa uvedie}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  zov\'9aeobecnite\'ben}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8257923\charrsid11145242 os\'9d a\~prenosite\'benos\'9d v\'fdsledkov anal\'fdzy}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . Vn\'fatorn\'e1
 a vonkaj\'9aia platnos\'9d }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11162956\charrsid11145242 farmako-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 ekonomick\'fdch}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11162956\charrsid11145242  rozborov
}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  zdravotnej starostlivosti je prinajmen\'9aom tak d\'f4le\'9eit\'e1 ako pri klinick\'fdch \'9at\'fadi\'e1ch. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 Napr\'edklad}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid8671414\charrsid11145242 :}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242  v\'fdsledky neskreslenej a\~vn\'fatorne platnej ekonomickej anal\'fdzy vykonanej v\~}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid8671414\charrsid11145242 
skupine mlad\'fdch pacientov nemusia by\'9d platn\'e9}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242  pre skupinu star\'9a\'edch pacientov. Na druhej strane \'9at\'fadie alebo modely s\~vysok\'fdm stup\'f2om vonkaj\'9aej platnosti  m
\'f4\'9eu ma\'9d n\'edzky stupe\'f2 vn\'fatornej platnosti z\~d\'f4vodu nedostatku spo\'beahliv\'fdch \'fadajov. Okrem toho existuj\'fa ve\'bek\'e9 rozdiely v\~odhadoch jednotkov\'fdch n\'e1kladov medzi krajinami a\~dokonca aj medzi r\'f4znymi \'fazemn
\'fdmi celkami v\~tej istej krajine. N\'e1kladov\'e1 efekt\'edvnos\'9d lie\'e8by sa takisto m\'f4\'9ee l\'ed\'9ai\'9d pri r\'f4znych indik\'e1ci\'e1ch, v\~rozdielnych podmienkach zdravotnej starostlivosti a\~v\~r\'f4znych krajin\'e1
ch. Preto je pri rozhodovacom procese potrebn\'e1 opatrnos\'9d pri interpret\'e1cii a\~pou\'9e\'edvan\'ed v\'fdsledkov }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid11162956\charrsid11145242 farmako-}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid16411968\charrsid11145242 ekonomick\'fdch}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid11162956\charrsid11145242  rozborov.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242  
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9001297\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
\par }\pard \ltrpar\s19\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid2957075 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid4736060\charrsid11145242 X}{\rtlch\fcs1 \ab\af0\afs28 
\ltrch\fcs0 \b\caps\fs28\insrsid5858158\charrsid11145242 I}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid4736060\charrsid11145242 . }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid16411968\charrsid11145242 Vplyv na zdravotn\'fa
 starostlivos\'9d}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid8671414\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx720\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8671414 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid8671414\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 11.1.}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\b\insrsid2957075\charrsid11145242 \tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 M}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 o\'9en\'fd rozpo\'e8tov\'fd vplyv na verejn\'e9 v\'fdda}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9796076\charrsid11145242 vky}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  na zdravotn\'fa starostlivos\'9d}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242  sa  analyz}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9796076\charrsid11145242 uje}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9796076\charrsid11145242  Do anal\'fdzy }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  sa }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9796076\charrsid11145242 zahrnie vplyv}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242  pou\'9eitia nov\'e9ho }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 lieku}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9138444\charrsid11145242  alebo inej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid12400204 novej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 technol\'f3gie }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
na ro\'e8n\'fd rozpo\'e8et a\~kumulat\'edvny vplyv po\'e8as }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 p\'e4\'9dro\'e8n\'e9ho obdobia. Odhady sa uv\'e1dzaj\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  v\~pr\'ed
pade r\'f4znych r\'fdchlost\'ed \'9a\'edrenia }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242  alebo inej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 
technol\'f3gie }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 a ke\'ef toto roz\'9a\'edrenie dosiahne plat\'f3. Na z\'e1klade ve\'bekosti relevantnej popul\'e1cie pacientov a\~o\'e8ak\'e1vanej r\'fdchlosti roz\'9airovania }{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242  alebo inej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 technol\'f3gie}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid8671414\charrsid11145242  sa odhadne aj}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  vplyv na verejn\'e9 v\'fdda}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9796076\charrsid11145242 vky}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  na zdravotn\'fa starostlivos\'9d (v r\'e1mci rozli\'e8n\'fdch rozpo\'e8tov na zdravotn\'fa starostlivos\'9d). D\'f4le\'9eit\'e9 je zd\'f4razni\'9d mo\'9en\'e9 \'faspory alebo dodato\'e8n\'e9 potrebn}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid8671414\charrsid11145242 \'e9 zdroje}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16661670\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242  ak sa o\'e8ak\'e1va, \'9ee nov\'fd}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 liek}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242  alebo in\'e1 }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2522957 nov\'e1 }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid4812959\charrsid11145242 technol\'f3gia }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 nahrad\'ed existuj\'faci. }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid8671414\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid16661670 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16661670\charrsid11145242 
\par }\pard \ltrpar\s19\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid16661670 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid2957075\charrsid11145242 V\'fdsledky }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid8671414\charrsid11145242 sa uv\'e1dzaj\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242  v\~prirodzen\'fdch ako aj pe\'f2a\'9en\'fdch jednotk\'e1ch. To umo\'9e\'f2uje }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\i\insrsid3032740\charrsid11145242 osob\'e1m}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242  prij\'edmaj\'facim rozhodnutia pos\'fadi\'9d, \'e8i je mo\'9en\'e9 zn\'ed\'9eenie prirodzen\'fdch jednotiek zdrojov (napr. nemocni\'e8n\'e9 l
\'f4\'9eka alebo \'e8as o\'9aetrovania) pou\'9ei\'9d v\~in\'fdch oblastiach zdravotnej starostlivosti a\~tak docieli\'9d pe\'f2a\'9en\'e9 \'faspory. Transparentnos\'9d anal\'fdzy vplyvov na rozpo\'e8et a\~pr\'edstup os\'f4b prij\'edmaj\'fa
cich rozhodnutia k\~modelu im umo\'9e\'f2uje \'9apecifickej\'9aie upravi\'9d v\'fdpo\'e8ty pre ich potreby. }{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid2957075\charrsid11145242 
\par }\pard \ltrpar\s19\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid2957075 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16661670\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 V\~z\'e1vislosti na povahe nov\'e9ho}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4812959\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 lieku}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9138444\charrsid11145242  alebo inej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid1194801 novej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid4812959\charrsid11145242 technol\'f3gie}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14813882\charrsid11145242  }
{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid8671414\charrsid11145242 je}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  d\'f4le\'9eit\'e9 pop\'edsa\'9d, \'e8i zavedenie nov\'e9ho }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 
lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242  alebo inej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 technol\'f3gie }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 bude vies\'9d k\~zv\'fd\'9a
eniu alebo zn\'ed\'9eeniu potreby na s\'favisiac}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16272789\charrsid11145242 u}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242   zdravotn}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16272789\charrsid11145242 
\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  starostlivos}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16272789\charrsid11145242 \'9d}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 .}{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 
\b\insrsid8671414\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid8671414 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid8671414\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid16661670\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 11.2.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16661670\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242 V\~rozbore sa vyhodnotia}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  predpoklady efekt\'edvneho zavedenia a\~po\'9eiadavk}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14306073\charrsid11145242 y}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  na n\'e1kladovo efekt\'edvne rutinn\'e9 pou\'9e\'edvanie nov\'e9ho}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14813882\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid9641321\charrsid11145242 lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9138444\charrsid11145242  alebo inej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11500599 novej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 technol\'f3
gie}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . Diskusia o\~predpo}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242 kladoch efekt\'edvneho zavedenia sa zamer}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid4528615\charrsid11145242 ia}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  na tie podmienky, ktor\'e9 s\'fa potrebn\'e9 na efekt\'edvne, n\'e1kladovo efekt\'edvne a\~soci\'e1lne prijate\'ben\'e9 pou\'9e\'edvanie nov\'e9ho}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14813882\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10176871\charrsid11145242  alebo }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11500599 
inej novej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 technol\'f3gie}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 . }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid14903958\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid16661670 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16661670\charrsid11145242 
\par }\pard \ltrpar\s19\qj \fi720\li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid16661670 {\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid16411968\charrsid11145242 Typick\'e9 predpoklady zah\'e0\'f2aj\'fa napr. potrebu v\'fd
cviku zdravotn\'edckeho person\'e1lu, vytvorenia nov\'fdch smern\'edc pre klinick\'fa prax a\~existenciu diagnostick\'fdch zariaden\'ed alebo efekt\'edvneho}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid14903958\charrsid11145242  darcovsk\'e9ho programu. }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid3162778\charrsid11145242 Do predpoklad}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid14818114\charrsid11145242 ov}{\rtlch\fcs1 \af0 \ltrch\fcs0 \i\insrsid3162778\charrsid11145242  sa zahrn\'fa aj}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \i\insrsid16411968\charrsid11145242  finan\'e8n\'e9 potreby na vytvorenie t\'fdchto predpokladov. }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid14903958\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid14903958 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid16661670\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid4736060 {\rtlch\fcs1 \af0 \ltrch\fcs0 \b\insrsid4736060\charrsid11145242 11.3.}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16661670\charrsid11145242 
\tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242 Analyzova\'9d je s\'fa\'e8asne potrebn\'e9 aj }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 rovnos\'9d a\~etick\'e9 ot\'e1zky t\'fdkaj\'face sa zavedenia nov\'e9ho }{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15037804\charrsid11145242  alebo inej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11500599 novej }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid9641321\charrsid11145242 technol\'f3gie }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  vz\'9dahuj\'face sa na metodol\'f3giu }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11162956\charrsid11145242 farmako-ekonomick\'e9ho rozboru}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242 v\~zdravotn\'edctve. Ak}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  zavedenie nov}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid3282488\charrsid11145242 \'e9ho}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14813882\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 lieku}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15037804\charrsid11145242 
 alebo inej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3282488\charrsid11145242 novej }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid9641321\charrsid11145242 technol\'f3gie }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242 ovplyvn\'ed}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  rovnos\'9d v\~oblasti zdravotn\'edctva (}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3282488\charrsid11145242 napr}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14818114\charrsid11145242 .}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242  pr\'edstup k\~zdravotnej starostlivosti, vyu\'9e\'edvanie zdravotnej starostlivosti alebo zn\'ed\'9eenie/zv\'fd\'9aenie nerovnosti v\~zdravotnom  stave), }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14903958\charrsid11145242 uved\'fa sa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  tieto vplyvy}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3282488\charrsid11145242  rovnako}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14818114\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3282488\charrsid11145242  ako aj}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10574811\charrsid11145242 ,}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3282488\charrsid11145242  a}{\rtlch\fcs1 
\af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 k cie\'beov\'e1 skupina pacientov predstavuje znev\'fdhodnen\'fa cie\'beov\'fa skupinu}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3282488\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  Okrem toho }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242 sa zd\'f4raznia}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  etick\'e9 aspekty, ktor\'e9 s\'fa v\'fdslovne zahrnut\'e9
 alebo predpokladan\'e9 v\~metodol\'f3gii }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11162956\charrsid11145242 farmako-}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 ekonomick}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11162956\charrsid11145242 
\'e9ho rozboru}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  (}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3282488\charrsid11145242 napr}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10574811\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242  v\'e1ha rovnosti).
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid6709787\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
\par }\pard \ltrpar\s19\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid16661670 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4736060\charrsid11145242 XII. }{\rtlch\fcs1 \ab\af0\afs28 
\ltrch\fcs0 \b\fs28\insrsid16661670\charrsid11145242 \tab }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid16411968\charrsid11145242 Z\'e1very}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid16411968\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid16411968\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid16661670\charrsid11145242 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16661670\charrsid11145242 \tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid3944645\charrsid11145242 \~Rozbor obsahuje}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14903958\charrsid11145242 v\'9aetky}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  z\'e1very anal\'fdzy}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242  v\~preh\'beadnej forme, ktor\'e9 s\'fa v}{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242 \~s\'falade s\~cie\'bemi}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242  a\~v\'fdsledkami uveden\'fdmi v rozbore}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 .
\par 
\par }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid2311294\charrsid11145242 
\par }\pard \ltrpar\s19\qj \fi-720\li720\ri0\widctlpar\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin720\itap0\pararsid6317861 {\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\fs28\insrsid4736060\charrsid6317861 XIII. }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 
\b\fs28\insrsid16661670\charrsid6317861 \tab }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid16411968\charrsid6317861 Etick\'fd}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid16411968\charrsid11145242  k\'f3dex  pre vykon\'e1
vanie a\~publikovanie v\'fdsledkov }{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid11283376\charrsid11145242 farmako-}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid16411968\charrsid11145242 ekonomick\'e9ho}{\rtlch\fcs1 
\ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid11283376\charrsid11145242  rozboru lieku}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 \b\caps\fs28\insrsid11674747\charrsid11145242  a\~inej technol\'f3gie}{\rtlch\fcs1 \ab\af0\afs28 \ltrch\fcs0 
\b\fs28\insrsid16411968\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid10974372 {\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid16411968\charrsid11145242 
\par }{\rtlch\fcs1 \ab\af0 \ltrch\fcs0 \b\insrsid16661670\charrsid11145242 
\par }\pard \ltrpar\s19\qj \li0\ri0\widctlpar\jclisttab\tx0\wrapdefault\aspalpha\aspnum\faauto\adjustright\rin0\lin0\itap0\pararsid15231472 {\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11283376\charrsid11145242 \tab }{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid16411968\charrsid11145242 Je d\'f4le\'9eit\'e9}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242 , aby }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11565497\charrsid11145242 autori}{\rtlch\fcs1 \af0 \ltrch\fcs0 
\insrsid14903958\charrsid11145242  anal\'fdz}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  disponoval}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11565497\charrsid11145242 i}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 
 adekv\'e1tnymi znalos\'9dami (}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11565497\charrsid11145242 napr}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid10574811\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11565497\charrsid11145242  }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid16411968\charrsid11145242 znalos\'9d metodol\'f3gie, vysok\'e1 profesion\'e1lna etika). Anal\'fdz}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11091767 y}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242  sa }{\rtlch\fcs1 \af0 
\ltrch\fcs0 \insrsid11565497\charrsid11145242 vykon\'e1va}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11091767 j\'fa}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11565497\charrsid11145242  }{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16411968\charrsid11145242 v\~s\'falade s
}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11565497\charrsid11145242 o z\'e1konmi}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid15231472  a in\'fdmi}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid11565497\charrsid11145242  v\'9aeobecne z\'e1v\'e4zn\'fdmi predpismi}{
\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid14903958\charrsid11145242 .}{\rtlch\fcs1 \af0 \ltrch\fcs0 \insrsid16661670\charrsid11145242 
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